Atypical hemolytic uremic syndrome in Brazil: clinical presentation, genetic findings and outcomes of a case series in adults and children treated with eculizumab

LMP Palma, RG Eick, GC Dantas… - Clinical Kidney …, 2021 - academic.oup.com
Background Atypical hemolytic uremic syndrome (aHUS) is characterized by
microangiopathic hemolytic anemia, thrombocytopenia and kidney injury caused by a …

Familial atypical hemolytic uremic syndrome: a review of its genetic and clinical aspects

F Bu, N Borsa, A Gianluigi… - Journal of Immunology …, 2012 - Wiley Online Library
Atypical hemolytic uremic syndrome (aHUS) is a rare renal disease (two per one million in
the USA) characterized by microangiopathic hemolytic anemia, thrombocytopenia, and …

[HTML][HTML] Genetic atypical hemolytic uremic syndrome in children: a 20-year experience from a tertiary center

C Maximiano, A Silva, I Duro, T Branco… - Brazilian Journal of …, 2021 - SciELO Brasil
Introduction: Atypical hemolytic uremic syndrome (aHUS) is a rare disorder characterized by
the triad of microangiopathic hemolytic anemia, thrombocytopenia, and acute kidney injury …

Safety and effectiveness of restrictive eculizumab treatment in atypical haemolytic uremic syndrome

KL Wijnsma, C Duineveld, EB Volokhina… - Nephrology Dialysis …, 2018 - academic.oup.com
Background Atypical haemolytic uremic syndrome (aHUS) is a rare but severe form of
thrombotic microangiopathy as a consequence of complement dysregulation. aHUS has a …

Eculizumab treatment and discontinuation in pediatric patients with atypical hemolytic uremic syndrome: a multicentric retrospective study

E Baskin, K Fidan, B Gulhan, K Gulleroglu… - Journal of …, 2022 - Springer
Introduction Eculizumab is effective treatment of pediatric atypical hemolytic uremic
syndrome (aHUS). However, the optimal duration of treatment is not clearly defined. The aim …

Eculizumab for the treatment of atypical hemolytic uremic syndrome: case report and revision of the literature

MH Vaisbich, LS Henriques, A Watanabe… - Brazilian Journal of …, 2013 - SciELO Brasil
Síndrome Hemolítico Urêmica atípica (SHUa), isto é, não associada à Escherichia coli,
produtora de Shiga toxina, é vista em 5% a 10% dos casos de Síndrome Hemolítico …

Eculizumab as first-line therapy for atypical hemolytic uremic syndrome

M Christmann, M Hansen, C Bergmann… - …, 2014 - publications.aap.org
Atypical hemolytic uremic syndrome (aHUS) is a genetic, life-threatening, chronic disease
that can affect patients of all ages. aHUS is caused by uncontrolled complement activation …

[HTML][HTML] Nephrotic syndrome associated with primary atypical hemolytic uremic syndrome

DC Bello-Marquez, JF Nieto-Rios… - Brazilian Journal of …, 2020 - SciELO Brasil
Primary atypical hemolytic-uremic syndrome is a rare disease characterized by non-immune
microangiopathic hemolytic anemia, thrombocytopenia, and renal dysfunction; it is related to …

Neonatal onset atypical hemolytic uremic syndrome successfully treated with eculizumab

N Besbas, B Gulhan, D Karpman, R Topaloglu… - Pediatric …, 2013 - Springer
Background Atypical hemolytic uremic syndrome (aHUS) is characterized by the triad of
microangiopathic hemolytic anemia, thrombocytopenia, and renal impairment. Neonatal …

Cryptic activity of atypical hemolytic uremic syndrome and eculizumab treatment

M Belingheri, I Possenti, F Tel, F Paglialonga… - …, 2014 - publications.aap.org
Atypical hemolytic uremic syndrome (aHUS) is a rare, life-threatening disease often related
to uncontrolled complement activation. The use of eculizumab has changed the …