Background The early life environment experienced by an individual in utero and during the
neonatal period is a major factor in shaping later life disease risk-including susceptibility to …

Strong evidence suggests that early-life exposures to suboptimal environmental factors,
including those in utero, influence our long-term metabolic health. This has been termed …

Research investigating the early programming of adult metabolic disease has in recent
years provided much mechanistic insight into how the early environment impacts on long …

The obesity epidemic has led to more women entering pregnancy overweight or obese. In
addition to adverse short‐term outcomes, maternal obesity and/or gestational diabetes …

The incidence of metabolic disease, including type 2 diabetes and obesity, has increased to
epidemic levels in recent years. A growing body of evidence suggests that the intrauterine …

The global obesity pandemic is often causally linked to marked changes in diet and lifestyle,
namely marked increases in dietary intakes of high-energy diets and concomitant reductions …

The intrauterine environment supports the development and health of offspring.
Perturbations to this environment can have detrimental effects on the fetus that have …

The global pandemic of obesity and type 2 diabetes is often causally linked to marked
changes in diet and lifestyle; namely marked increases in dietary intakes of high energy …

Recent evidence demonstrates important maternal effects on an offspring's risk of
developing metabolic disease. These effects extend across the full range of maternal …

The environment in utero and in early neonatal life may induce a permanent response in the
fetus and the newborn, leading to enhanced susceptibility to later diseases. This review …