Background SCNT (somatic cell nuclear transfer) is of great significance to biological
research and also to the livestock breeding. However, the survival rate of the SCNT cloned …

To date, the genome-wide DNA methylation status of cloned pigs has not been investigated.
Due to the relatively low success rate of pig cloning by somatic cell nuclear transfer, a better …

Animal breeding via Somatic Cell Nuclear Transfer (SCNT) has enormous potential in
agriculture and biomedicine. However, concerns about whether SCNT animals are as …

Many observations have been made on cloned embryos and on adult clones by somatic cell
nuclear transfer (SCNT), but it is still unclear whether the progeny of cloned animals is …

Many studies have proved that DNA methylation can regulate gene expression and further
affect skeletal muscle growth and development of pig, whereas the mechanisms of how DNA …

Somatic cell nuclear transfer (SCNT) has been used for the cloning of various mammals.
However, the rates of successful, healthy birth are generally poor. To improve cloning …

The domestic goat (Capra aegagrus hircus), a mammalian species with high genetic merit
for production of milk and meat, can be a tremendously valuable tool for transgenic …

Swine is a common model organism for biomedical research. Epigenetic reprogramming in
somatic cell nuclear transfer (SCNT) embryos does not fully recapitulate the natural DNA …

Epigenetic reprogramming confers totipotency even during somatic cell nuclear transfer
(SCNT), which has been used to clone various animal species. However, as even …

Somatic cloning has had a significant impact on the life sciences and is important in a variety
of processes, including medical research and animal production. However, the application …