[HTML][HTML] Analysis pipelines and packages for Infinium HumanMethylation450 BeadChip (450k) data

TJ Morris, S Beck - Methods, 2015 - Elsevier
Abstract The Illumina HumanMethylation450 BeadChip has become a popular platform for
interrogating DNA methylation in epigenome-wide association studies (EWAS) and related …

A coherent approach for analysis of the Illumina HumanMethylation450 BeadChip improves data quality and performance in epigenome-wide association studies

B Lehne, AW Drong, M Loh, W Zhang, WR Scott… - Genome biology, 2015 - Springer
DNA methylation plays a fundamental role in the regulation of the genome, but the optimal
strategy for analysis of genome-wide DNA methylation data remains to be determined. We …

[HTML][HTML] Identification of polymorphic and off-target probe binding sites on the Illumina Infinium MethylationEPIC BeadChip

DL McCartney, RM Walker, SW Morris, AM McIntosh… - Genomics data, 2016 - Elsevier
Genome-wide analysis of DNA methylation has now become a relatively inexpensive
technique thanks to array-based methylation profiling technologies. The recently developed …

IMA: an R package for high-throughput analysis of Illumina's 450K Infinium methylation data

D Wang, L Yan, Q Hu, LE Sucheston, MJ Higgins… - …, 2012 - academic.oup.com
The Illumina Infinium HumanMethylation450 BeadChip is a newly designed high-density
microarray for quantifying the methylation level of over 450 000 CpG sites within human …

A Comparison of the Whole Genome Approach of MeDIP-Seq to the Targeted Approach of the Infinium HumanMethylation450 BeadChip® for Methylome Profiling

C Clark, P Palta, CJ Joyce, C Scott, E Grundberg… - PloS one, 2012 - journals.plos.org
DNA methylation is one of the most studied epigenetic marks in the human genome, with the
result that the desire to map the human methylome has driven the development of several …

Additional annotation enhances potential for biologically-relevant analysis of the Illumina Infinium HumanMethylation450 BeadChip array

EM Price, AM Cotton, LL Lam, P Farré, E Emberly… - Epigenetics & …, 2013 - Springer
Background Measurement of genome-wide DNA methylation (DNAm) has become an
important avenue for investigating potential physiologically-relevant epigenetic changes …

Critical evaluation of the Illumina MethylationEPIC BeadChip microarray for whole-genome DNA methylation profiling

R Pidsley, E Zotenko, TJ Peters, MG Lawrence… - Genome biology, 2016 - Springer
Background In recent years the Illumina HumanMethylation450 (HM450) BeadChip has
provided a user-friendly platform to profile DNA methylation in human samples. However …

A systematic study of normalization methods for Infinium 450K methylation data using whole-genome bisulfite sequencing data

T Wang, W Guan, J Lin, N Boutaoui, G Canino, J Luo… - Epigenetics, 2015 - Taylor & Francis
DNA methylation plays an important role in disease etiology. The Illumina Infinium
HumanMethylation450 (450K) BeadChip is a widely used platform in large-scale …

missMethyl: an R package for analyzing data from Illumina's HumanMethylation450 platform

B Phipson, J Maksimovic, A Oshlack - Bioinformatics, 2015 - academic.oup.com
DNA methylation is one of the most commonly studied epigenetic modifications due to its
role in both disease and development. The Illumina HumanMethylation450 BeadChip is a …

RELIC: a novel dye-bias correction method for Illumina Methylation BeadChip

Z Xu, SAS Langie, P De Boever, JA Taylor, L Niu - BMC genomics, 2017 - Springer
Abstract Background The Illumina Infinium HumanMethylation450 BeadChip and its
successor, Infinium MethylationEPIC BeadChip, have been extensively utilized in …