The early-life exposome influences future health and accelerated biological aging has been
proposed as one of the underlying biological mechanisms. We investigated the association …

Background Air pollution is associated with accelerated biological ages determined by DNA
methylation (DNAm) patterns, imposing further risks of age-related adverse effects …

Although universal and unavoidable, ageing does not occur in a uniform way. Ageing is a
complex phenotype responsive to a plethora of environmental stressors from early life …

Long-term exposure to air pollution is associated with age-related diseases. We explored
the association between accelerated biological aging and air pollution, a potential …

Abstract Purpose of Review There is interest in evaluating the developmental origins of
health and disease (DOHaD) which emphasizes the role of prenatal and early-life …

Background Epigenetic age, as defined by DNA methylation, may be influenced by air
pollution exposure. Objective To evaluate the relationship between NO 2, particulate matter …

Age-related diseases account for almost half of all diseases among adults worldwide, and
their incidence is substantially affected by the exposome, which is the sum of all exogenous …

Epigenetic aging biomarkers are associated with increased morbidity and mortality. We
evaluated if occupational exposure to three established chemical carcinogens is associated …

Environmental exposures during early life play a critical role in life-course health, yet the
molecular phenotypes underlying environmental effects on health are poorly understood. In …

Biological age, measured via epigenetic clocks, offers a unique and useful tool for
prevention scientists to explore the short-and long-term implications of age deviations for …