[HTML][HTML] DNA methylation of the first exon is tightly linked to transcriptional silencing
F Brenet, M Moh, P Funk, E Feierstein, AJ Viale… - PloS one, 2011 - journals.plos.org
Tissue specific patterns of methylated cytosine residues vary with age, can be altered by
environmental factors, and are often abnormal in human disease yet the cellular …
environmental factors, and are often abnormal in human disease yet the cellular …
Establishing, maintaining and modifying DNA methylation patterns in plants and animals
JA Law, SE Jacobsen - Nature Reviews Genetics, 2010 - nature.com
Cytosine DNA methylation is a stable epigenetic mark that is crucial for diverse biological
processes, including gene and transposon silencing, imprinting and X chromosome …
processes, including gene and transposon silencing, imprinting and X chromosome …
Conservation and divergence of methylation patterning in plants and animals
Cytosine DNA methylation is a heritable epigenetic mark present in many eukaryotic
organisms. Although DNA methylation likely has a conserved role in gene silencing, the …
organisms. Although DNA methylation likely has a conserved role in gene silencing, the …
Putting DNA methylation in context: from genomes to gene expression in plants
CE Niederhuth, RJ Schmitz - Biochimica et Biophysica Acta (BBA)-Gene …, 2017 - Elsevier
Plant DNA methylation is its own language, interpreted by the cell to maintain silencing of
transposons, facilitate chromatin structure, and to ensure proper expression of some genes …
transposons, facilitate chromatin structure, and to ensure proper expression of some genes …
[HTML][HTML] Global loss of DNA methylation uncovers intronic enhancers in genes showing expression changes
Background Gene expression is epigenetically regulated by a combination of histone
modifications and methylation of CpG dinucleotides in promoters. In normal cells, CpG-rich …
modifications and methylation of CpG dinucleotides in promoters. In normal cells, CpG-rich …
[HTML][HTML] Whole-genome bisulfite sequencing of multiple individuals reveals complementary roles of promoter and gene body methylation in transcriptional regulation
Background DNA methylation is an important type of epigenetic modification involved in
gene regulation. Although strong DNA methylation at promoters is widely recognized to be …
gene regulation. Although strong DNA methylation at promoters is widely recognized to be …
[HTML][HTML] Dynamic DNA methylation in plant growth and development
A Bartels, Q Han, P Nair, L Stacey, H Gaynier… - International journal of …, 2018 - mdpi.com
DNA methylation is an epigenetic modification required for transposable element (TE)
silencing, genome stability, and genomic imprinting. Although DNA methylation has been …
silencing, genome stability, and genomic imprinting. Although DNA methylation has been …
The methylome: approaches for global DNA methylation profiling
S Beck, VK Rakyan - Trends in Genetics, 2008 - cell.com
DNA methylation plays a critical role in genome function both in health and disease. Almost
60 years after the discovery of 5-methyl cytosine and∼ 25 years since the discovery that …
60 years after the discovery of 5-methyl cytosine and∼ 25 years since the discovery that …
[HTML][HTML] Profiling genome-wide DNA methylation
DNA methylation is an epigenetic modification that plays an important role in regulating
gene expression and therefore a broad range of biological processes and diseases. DNA …
gene expression and therefore a broad range of biological processes and diseases. DNA …
Dynamic DNA methylation across diverse human cell lines and tissues
As studies of DNA methylation increase in scope, it has become evident that methylation has
a complex relationship with gene expression, plays an important role in defining cell types …
a complex relationship with gene expression, plays an important role in defining cell types …