Maternal high-fat diet alters methylation and gene expression of dopamine and opioid-related genes

Z Vucetic, J Kimmel, K Totoki, E Hollenbeck… - …, 2010 - academic.oup.com
Maternal obesity during pregnancy increases the risk of obesity in the offspring. Obesity,
arising from an imbalance of energy intake and expenditure, can be driven by the ingestion …

Methyl donor supplementation blocks the adverse effects of maternal high fat diet on offspring physiology

JL Carlin, R George, TM Reyes - PloS one, 2013 - journals.plos.org
Maternal consumption of a high fat diet during pregnancy increases the offspring risk for
obesity. Using a mouse model, we have previously shown that maternal consumption of a …

Maternal high‐fat diet and obesity impact palatable food intake and dopamine signaling in nonhuman primate offspring

HM Rivera, P Kievit, MA Kirigiti, LA Bauman… - …, 2015 - Wiley Online Library
Objective To utilize a nonhuman primate model to examine the impact of maternal high‐fat
diet (HFD) consumption and pre‐pregnancy obesity on offspring intake of palatable food …

[HTML][HTML] Maternal high fat diets: Impacts on offspring obesity and epigenetic hypothalamic programming

B Harmancıoğlu, S Kabaran - Frontiers in genetics, 2023 - frontiersin.org
Maternal high-fat diet (HFD) during pregnancy is associated with rapid weight gain and fetal
fat mass increase at an early stage. Also, HFD during pregnancy can cause the activation of …

Maternal high-fat diet acts as a stressor increasing maternal glucocorticoids' signaling to the fetus and disrupting maternal behavior and brain activation in C57BL/6J …

V Bellisario, P Panetta, G Balsevich, V Baumann… - …, 2015 - Elsevier
Maternal diet during pregnancy can impact maternal behavior as well as the intrauterine
environment, playing a critical role in programming offspring's physiology. In a preliminary …

Maternal high-fat diet associated with altered gene expression, DNA methylation, and obesity risk in mouse offspring

MR Keleher, R Zaidi, S Shah, ME Oakley, C Pavlatos… - PloS one, 2018 - journals.plos.org
We investigated maternal obesity in inbred SM/J mice by assigning females to a high-fat diet
or a low-fat diet at weaning, mating them to low-fat-fed males, cross-fostering the offspring to …

Maternal high-fat diet during lactation reprograms the dopaminergic circuitry in mice

RN Lippert, S Hess, P Klemm… - The Journal of …, 2020 - Am Soc Clin Investig
The maternal perinatal environment modulates brain formation, and altered maternal
nutrition has been linked to the development of metabolic and psychiatric disorders in the …

Maternal high-fat intake alters presynaptic regulation of dopamine in the nucleus accumbens and increases motivation for fat rewards in the offspring

L Naef, L Moquin, G Dal Bo, B Giros, A Gratton… - Neuroscience, 2011 - Elsevier
High caloric intake during early postnatal development can have long term consequences
for the offspring. We previously reported that the adult offspring of dams fed a high-fat diet …

Maternal and postweaning diet interaction alters hypothalamic gene expression and modulates response to a high-fat diet in male offspring

KC Page, RE Malik, JA Ripple… - American Journal of …, 2009 - journals.physiology.org
Epidemiological data and results from animal studies indicate that imbalances in maternal
nutrition impact the expression of metabolic disorders in the offspring. We tested the …

DNA hypomethylation of inflammation-associated genes in adipose tissue of female mice after multigenerational high fat diet feeding

Y Ding, J Li, S Liu, L Zhang, H Xiao, H Chen… - International Journal of …, 2014 - nature.com
Objective: Maternal obesity significantly increases the susceptibility of offspring to develop
obesity and chronic diseases in adulthood. The offspring of obese mothers are shown to …