Melatonin (MEL), an indoleamine hormone synthesized in almost all organisms including
humans, has been the object of a considerable body of research due to its pleiotropic …

Melatonin, a tryptophan-derived neurohormone found in animals, plants, and microbes,
participates in various biological and physiological functions. Among other properties …

Melatonin is a pleiotropic neurohormone found in different animal, plant, and microorganism
species. It is a product resulting from tryptophan metabolism in the pineal gland and is …

Melatonin (N-acetyl-5-methoxytryptamine)(MEL) is an indolerelated neurohormone secreted
mainly by the pineal gland. Although MEL freely diffuses across all biological membranes …

Abstract Melatonin (N-acetyl-5-methoxytryptamine) is a circadian hormone produced in
vertebrates by the pineal gland and other organs. Melatonin is believed to influence immune …

In all mammals, the circulating pool of MLTs is synthesized in the pineal gland during the
night's darkness hours. Its main function is synchronizing the organism in the photoperiod. In …

Regarded as the circadian hormone in mammals, melatonin is a highly conserved molecule,
present in nearly all species. In this review, we discuss the role of this indolamine and its …

Melatonin is a hormone produced at night in the pineal gland and its production declines
with age. Plasma concentrations of melatonin gradually decline after the third decade of life …

Melatonin is a neurohormone that has attracted a great deal of attention, being frequently
investigated in recent years. Due to its wide-spectrum of properties, melatonin has been …

Melatonin modulates a wide range of physiological functions with pleiotropic effects on the
immune system. Despite the large number of reports implicating melatonin as an …