Macrophages play crucial roles in abdominal aortic aneurysm (AAA) formation through the
inflammatory response and extracellular matrix degradation; therefore, regulating …

Objective—Abdominal aortic aneurysm is caused by the accumulation of inflammatory cells
in the aortic wall. Our recent studies demonstrated that inhibition of Notch signaling …

Background and aims Abdominal aortic aneurysm (AAA) is a common disease; however, its
exact pathogenesis remains unknown, and no specific medical therapies are available …

Background Development of abdominal aortic aneurysm (AAA) is associated with
proinflammatory cytokines including interleukin‐12 (IL12). Deficiency of interleukin 12p40 …

Although the pathogenesis of abdominal aortic aneurysm (AAA) remains unclear, evidence
is accumulating to support a central role for inflammation. Inflammatory responses are …

Abstract Abdominal Aortic Aneurysms (AAA) remain a clinically devastating disease with no
effective medical treatment therapy. AAAs are characterized by immune cell infiltration …

Macrophages play an important role in the inflammatory process that contributes to the
development of abdominal aortic aneurysm (AAA). Studies of human and mouse AAA tissue …

Objective—Abdominal aortic aneurysms (AAAs) are common, but their exact pathogenesis
remains unknown and no specific medical therapies are available. We sought to evaluate …

Objective—Inflammation occurs during the progression of abdominal aortic aneurysm (AAA).
IL (interleukin)-33 is a pleiotropic cytokine with multiple immunomodulatory effects, yet its …

Background: The formation and rupture of aneurysms is a reversible process involving the
destruction and repair of smooth muscle cells, and the proliferation of vascular smooth …