Cerebral oxygen extraction fraction (OEF): Comparison of challenge-free gradient echo QSM+qBOLD (QQ) with 15O PET in healthy adults

J Cho, J Lee, H An, MS Goyal, Y Su… - Journal of Cerebral …, 2021 - journals.sagepub.com
We aimed to validate oxygen extraction fraction (OEF) estimations by quantitative
susceptibility mapping plus quantitative blood oxygen-level dependence (QSM+ qBOLD, or …

Oxygen extraction fraction measurement using quantitative susceptibility mapping: comparison with positron emission tomography

K Kudo, T Liu, T Murakami, J Goodwin… - Journal of Cerebral …, 2016 - journals.sagepub.com
The purposes of this study are to establish oxygen extraction fraction (OEF) measurements
using quantitative susceptibility mapping (QSM) of magnetic resonance imaging (MRI), and …

Cerebral OEF quantification: A comparison study between quantitative susceptibility mapping and dual‐gas calibrated BOLD imaging

Y Ma, H Sun, J Cho, EL Mazerolle… - Magnetic resonance …, 2020 - Wiley Online Library
Purpose To compare regional oxygen extraction fraction (OEF) and cerebral metabolic rate
of oxygen consumption (CMRO2) quantified from the microvascular quantitative …

[HTML][HTML] Quantification of brain oxygen extraction and metabolism with [15O]-gas PET: A technical review in the era of PET/MRI

AP Fan, H An, F Moradi, J Rosenberg, Y Ishii, T Nariai… - Neuroimage, 2020 - Elsevier
Oxygen extraction fraction (OEF) and the cerebral metabolic rate of oxygen (CMRO 2) are
key cerebral physiological parameters to identify at-risk cerebrovascular patients and …

Noninvasive assessment of oxygen extraction fraction in chronic ischemia using quantitative susceptibility mapping at 7 Tesla

I Uwano, K Kudo, R Sato, K Ogasawara, H Kameda… - Stroke, 2017 - Am Heart Assoc
Background and Purpose—The oxygen extraction fraction (OEF) is an effective metric to
evaluate metabolic reserve in chronic ischemia. However, OEF is considered to be …

Validation of T2‐based oxygen extraction fraction measurement with 15O positron emission tomography

D Jiang, S Deng, CG Franklin, M O'Boyle… - Magnetic resonance …, 2021 - Wiley Online Library
Purpose To evaluate the accuracy of T2‐based whole‐brain oxygen extraction fraction
(OEF) estimation by comparing it with gold standard 15O‐PET measurements. Methods …

Mapping of cerebral oxygen extraction fraction changes with susceptibility-weighted phase imaging

Y Zaitsu, K Kudo, S Terae, R Yazu, K Ishizaka… - Radiology, 2011 - pubs.rsna.org
Purpose To develop a map to detect changes in oxygen extraction fraction (OEF) utilizing
susceptibility-weighted (SW) phase images and to correlate such changes in OEF with those …

Quantification of brain oxygen extraction fraction using QSM and a hyperoxic challenge

Y Ma, EL Mazerolle, J Cho, H Sun… - Magnetic resonance …, 2020 - Wiley Online Library
Purpose To use hyperoxia in combination with QSM to quantify microvascular oxygen
extraction fraction (OEF) and cerebral metabolic rate of oxygen (CMRO2) in healthy subjects …

Baseline oxygenation in the brain: correlation between respiratory-calibration and susceptibility methods

AP Fan, A Schäfer, L Huber, L Lampe, S von Smuda… - Neuroimage, 2016 - Elsevier
New MRI methods for noninvasive imaging of baseline oxygen extraction fraction (OEF) in
the brain show great promise. Quantitative O 2 imaging (QUO2) applies a biophysical model …

Cerebral oxygen extraction fraction MRI: Techniques and applications

D Jiang, H Lu - Magnetic resonance in medicine, 2022 - Wiley Online Library
The human brain constitutes 2% of the body's total mass but uses 20% of the oxygen. The
rate of the brain's oxygen utilization can be derived from a knowledge of cerebral blood flow …