There is currently insufficient knowledge of gestational age dependent medicine disposition
in neonates. Accordingly, the use of off‐label medication, ie, use of medicines outside its …

Background Frequent prescription of medication in an unapproved manner (off‐label or
unlicensed) in the neonatal setting is a result of the limited availability of adequately studied …

Pharmacotherapy of neonates is complex and marked to a large extent of off-label use. The
implementation of the Paediatric Regulation (2007) gave hope for a change in the safety …

Objective A cross-sectional study was carried out to evaluate the practice of unlicensed and
off-label drug prescribing/dispensing in children and neonates by physicians and clinical …

Objectives To characterise neonatal hospital drug use and to compare the availability of
drug information between Estonian Summaries of Product Characteristics (SPCs) and other …

Health-care professionals who prescribe medicines have the professional duty to choose
medicines that are in the best interest of their individual patient, irrespective if that patient is …

The lack of specific drugs and labelling recommendations for the neonatal population is a
long-standing problem throughout the world. With the introduction of the Paediatric …

Objective Many drugs used for children are not licensed or are used off-label. An increased
risk of medication errors and unexpected adverse drug reactions (ADR) associated with off …

This review aims to give an updated overview of the worldwide situation of off-label and
unlicensed drug use in the paediatric field, also taking into account the safety of this kind of …

Background Off-label uses of medicines are common in pediatrics. The literature reports that
at least one-third of children in hospital and up to 90% of newborns in neonatal intensive …