Monoclonal antibodies for moderate-to-severe atopic dermatitis: a look at phase III and beyond

E David, K Hawkins, N Shokrian… - Expert Opinion on …, 2024 - Taylor & Francis
Introduction The understanding of atopic dermatitis (AD) pathogenesis has rapidly
expanded in recent years, catalyzing the development of new targeted monoclonal antibody …

Monoclonal antibodies for atopic dermatitis: Progress and potential

PP Vakharia, JI Silverberg - BioDrugs, 2017 - Springer
Atopic dermatitis (AD) is a complex and heterogeneous inflammatory skin disorder with a
profound symptom and lesional burden. Moderate-to-severe AD is particularly challenging …

Atopic dermatitis: a review of evolving targeted therapies

K Kalamaha, E Reis, S Newton, C Roche… - Expert review of …, 2019 - Taylor & Francis
Introduction: Atopic dermatitis (AD) is a chronic inflammatory skin condition, affecting a
significant number of patients of all ages. As we learn more about the pathogenesis of AD …

Past, present, and future for biologic intervention in atopic dermatitis

MD Howell, ML Parker, T Mustelin, K Ranade - Allergy, 2015 - Wiley Online Library
Atopic dermatitis (AD) is a debilitating disease that significantly alters the quality of life for
one in four children and one in 10 adults. Current management of AD utilizes combinations …

Current and future monoclonal antibodies in the treatment of atopic dermatitis

PIF Chun, H Lehman - Clinical reviews in allergy & immunology, 2020 - Springer
Atopic dermatitis is a common immunologic skin disease. Mild atopic dermatitis can be
managed with emollients and topical therapies such as low potency topical steroids, which …

An overview of new and emerging antibody therapies for moderate-severe atopic dermatitis in adults

V Picone, Y Vallone, C Patruno… - Expert Review of …, 2023 - Taylor & Francis
Introduction A comprehensive review of the English-language medical literature was
performed searching for ongoing and closed clinical trials concerning new and emerging …

Advances in the pathophysiology of atopic dermatitis revealed by novel therapeutics and clinical trials

X Yang, N Kambe, R Takimoto-Ito… - Pharmacology & …, 2021 - Elsevier
Atopic dermatitis (AD) is an inflammatory skin disease arising from a complex interplay of
genetic, immune, and environmental factors. The development and successful marketing of …

Monoclonal antibodies for the treatment of atopic dermatitis

Y Renert-Yuval, E Guttman-Yassky - Current opinion in allergy …, 2018 - journals.lww.com
Monoclonal antibodies for the treatment of atopic dermatitis : Current Opinion in Allergy and
Clinical Immunology Monoclonal antibodies for the treatment of atopic dermatitis : Current …

Novel investigational therapies for atopic dermatitis

KS Ibler, GBE Jemec - Expert Opinion on Investigational Drugs, 2015 - Taylor & Francis
Introduction: Atopic dermatitis (AD) is a common skin disease. Although most patients are
well served by existing therapies, a subset of patients with severe AD are still not adequately …

Emerging systemic therapies for atopic dermatitis: biologics

KB Nusbaum, CM Nguyen… - Journal of Dermatological …, 2022 - Taylor & Francis
Background The mainstay of atopic dermatitis treatment has been largely unchanged over
the last few decades. With improved understanding of the immunologic pathways underlying …