[HTML][HTML] An overview of epigenetics in obesity: the role of lifestyle and therapeutic interventions

AM Mahmoud - International journal of molecular sciences, 2022 - mdpi.com
Obesity has become a global epidemic that has a negative impact on population health and
the economy of nations. Genetic predispositions have been demonstrated to have a …

[HTML][HTML] Recent developments on the role of epigenetics in obesity and metabolic disease

SJ van Dijk, RL Tellam, JL Morrison, BS Muhlhausler… - Clinical …, 2015 - Springer
The increased prevalence of obesity and related comorbidities is a major public health
problem. While genetic factors undoubtedly play a role in determining individual …

The role of epigenetics in the development of obesity

A Obri, D Serra, L Herrero, P Mera - Biochemical Pharmacology, 2020 - Elsevier
The epidemic of obesity has become pandemic, putting a significant burden on the world's
healthcare system. While the heritability of the disease is high, all the identified genetic …

Epigenetic regulation in obesity

C Lavebratt, M Almgren, TJ Ekström - International journal of obesity, 2012 - nature.com
The availability to the DNA strand and the activity of the transcription machinery is crucial for
the cell to use the information in the DNA. The epigenetic mechanisms DNA methylation …

Epigenetic regulation of energy metabolism in obesity

W Gao, JL Liu, X Lu, Q Yang - Journal of molecular cell biology, 2021 - academic.oup.com
Obesity has reached epidemic proportions globally. Although modern adoption of a
sedentary lifestyle coupled with energy-dense nutrition is considered to be the main cause …

[HTML][HTML] Recent progress in epigenetics of obesity

FY Wu, RX Yin - Diabetology & Metabolic Syndrome, 2022 - Springer
Nowadays, obesity is one of the largest public health problems worldwide. In the last few
decades, there has been a marked increase in the obesity epidemic and its related …

Epigenetics and obesity

J Campión, F Milagro, JA Martínez - Progress in molecular biology and …, 2010 - Elsevier
The etiology of obesity is multifactorial, involving complex interactions among the genetic
makeup, neuroendocrine status, fetal programming, and different unhealthy environmental …

[HTML][HTML] Genetics and epigenetics in the obesity phenotyping scenario

K Trang, SFA Grant - Reviews in endocrine and metabolic disorders, 2023 - Springer
Obesity is a common complex trait that elevates the risk for various diseases, including type
2 diabetes and cardiovascular disease. A combination of environmental and genetic factors …

What obesity research tells us about epigenetic mechanisms

NA Youngson, MJ Morris - Philosophical Transactions of …, 2013 - royalsocietypublishing.org
The pathophysiology of obesity is extremely complex and is associated with extensive gene
expression changes in tissues throughout the body. This situation, combined with the fact …

Epigenetics of obesity

A Lopomo, E Burgio, L Migliore - Progress in molecular biology and …, 2016 - Elsevier
Obesity is a metabolic disease, which is becoming an epidemic health problem: it has been
recently defined in terms of Global Pandemic. Over the years, the approaches through …