[HTML][HTML] Melatonin's impact on antioxidative and anti-inflammatory reprogramming in homeostasis and disease
DM Chitimus, MR Popescu, SE Voiculescu… - Biomolecules, 2020 - mdpi.com
There is a growing consensus that the antioxidant and anti-inflammatory properties of
melatonin are of great importance in preserving the body functions and homeostasis, with …
melatonin are of great importance in preserving the body functions and homeostasis, with …
[HTML][HTML] Melatonin: highlighting its use as a potential treatment for SARS-CoV-2 infection
Numerous pharmaceutical drugs have been repurposed for use as treatments for COVID-19
disease. These drugs have not consistently demonstrated high efficacy in preventing or …
disease. These drugs have not consistently demonstrated high efficacy in preventing or …
COVID-19: Melatonin as a potential adjuvant treatment
R Zhang, X Wang, L Ni, X Di, B Ma, S Niu, C Liu… - Life sciences, 2020 - Elsevier
This article summarizes the likely benefits of melatonin in the attenuation of COVID-19
based on its putative pathogenesis. The recent outbreak of COVID-19 has become a …
based on its putative pathogenesis. The recent outbreak of COVID-19 has become a …
[HTML][HTML] Potential utility of melatonin in deadly infectious diseases related to the overreaction of innate immune response and destructive inflammation: focus on …
DX Tan, R Hardeland - Melatonin Research, 2020 - melatonin-research.net
The high mortality of deadly virus infectious diseases including SARS, MERS, COVID-19,
and avian flu is often caused by the uncontrolled innate immune response and destructive …
and avian flu is often caused by the uncontrolled innate immune response and destructive …
[HTML][HTML] Possible application of melatonin in long COVID
DP Cardinali, GM Brown, SR Pandi-Perumal - Biomolecules, 2022 - mdpi.com
Clinical sequelae and symptoms for a considerable number of COVID-19 patients can linger
for months beyond the acute stage of SARS-CoV-2 infection,“long COVID”. Among the long …
for months beyond the acute stage of SARS-CoV-2 infection,“long COVID”. Among the long …
Mechanisms and clinical evidence to support melatonin's use in severe COVID-19 patients to lower mortality
The fear of SARS-CoV-2 infection is due to its high mortality related to seasonal flu. To date,
few medicines have been developed to significantly reduce the mortality of the severe …
few medicines have been developed to significantly reduce the mortality of the severe …
[HTML][HTML] Can melatonin be a potential “silver bullet” in treating COVID-19 patients?
DP Cardinali, GM Brown, SR Pandi-Perumal - Diseases, 2020 - mdpi.com
The therapeutic potential of melatonin as a chronobiotic cytoprotective agent to counteract
the consequences of COVID-19 infections has been advocated. Because of its wide-ranging …
the consequences of COVID-19 infections has been advocated. Because of its wide-ranging …
[HTML][HTML] Targeting host defense system and rescuing compromised mitochondria to increase tolerance against pathogens by melatonin may impact outcome of deadly …
DX Tan, R Hardeland - Molecules, 2020 - mdpi.com
Fighting infectious diseases, particularly viral infections, is a demanding task for human
health. Targeting the pathogens or targeting the host are different strategies, but with an …
health. Targeting the pathogens or targeting the host are different strategies, but with an …
[HTML][HTML] Therapeutic algorithm for use of melatonin in patients with COVID-19
The coronavirus, COVID-19, has infected hundreds of thousands and killed tens of
thousands of individuals worldwide. This highly infectious condition continues to ravage the …
thousands of individuals worldwide. This highly infectious condition continues to ravage the …
[HTML][HTML] Clinical trials for use of melatonin to fight against COVID-19 are urgently needed
The recent pandemic of COVID-19 has already infected millions of individuals and has
resulted in the death of hundreds of thousands worldwide. Based on clinical features …
resulted in the death of hundreds of thousands worldwide. Based on clinical features …