Treatment of seizures in the neonate: Guidelines and consensus‐based recommendations—Special report from the ILAE Task Force on Neonatal Seizures

RM Pressler, NS Abend, S Auvin, G Boylan, F Brigo… - …, 2023 - Wiley Online Library
Seizures are common in neonates, but there is substantial management variability. The
Neonatal Task Force of the International League Against Epilepsy (ILAE) developed …

Pharmacotherapy for neonatal seizures: current knowledge and future perspectives

MD Donovan, BT Griffin, L Kharoshankaya, JF Cryan… - Drugs, 2016 - Springer
Seizures are the most common neurological emergencies in the neonatal period and are
associated with poor neurodevelopmental outcomes. Seizures affect up to five per 1000 …

Systematic review of neonatal seizure management strategies provides guidance on anti‐epileptic treatment

L Hellström‐Westas, G Boylan, J Ågren - Acta paediatrica, 2015 - Wiley Online Library
There is a lack of scientific evidence to support the best management of neonatal seizures.
Current strategies for neonatal seizure management were investigated by analysis of all …

Pharmacological treatment of neonatal seizures: a systematic review

LA Slaughter, AD Patel… - Journal of child …, 2013 - journals.sagepub.com
Pharmacologic treatment options for neonatal seizures have expanded over the past 2
decades, and there is no consensus on optimal treatment strategy. We systematically …

Anticonvulsants for neonates with seizures

D Booth, DJ Evans - Cochrane Database of Systematic …, 2004 - cochranelibrary.com
Background Neonatal seizures are a common problem and most neonates with seizures are
treated with anticonvulsants. There is wide variation in clinical practice in both diagnosis and …

Treatment of neonatal seizures: comparison of treatment pathways from 11 neonatal intensive care units

JC Keene, LA Morgan, NS Abend, SV Bates… - Pediatric …, 2022 - Elsevier
Objective Seizures are a common neonatal neurologic emergency. Many centers have
developed pathways to optimize management. We evaluated neonatal seizure management …

Neonatal seizures: multicenter variability in current treatment practices

AI Bartha, J Shen, KH Katz, RE Mischel, KR Yap… - Pediatric …, 2007 - Elsevier
Standardized approaches to the treatment of neonatal seizures remain undeveloped. We
assessed the type and number of anticonvulsants selected, blood levels attained, and …

Neonatal seizures: treatment and treatment variability in 31 United States pediatric hospitals

HK Blume, MM Garrison… - Journal of child …, 2009 - journals.sagepub.com
Neonatal seizures are one of the most common neurological disorders in infants. However,
the optimal treatment strategy for neonatal seizures remains controversial and there is little …

The use of phenobarbital and other anti-seizure drugs in newborns

M El-Dib, JS Soul - Seminars in Fetal and Neonatal Medicine, 2017 - Elsevier
Neonatal seizures constitute the most frequent presenting neurologic sign encountered in
the neonatal intensive care unit. Despite limited efficacy and safety data, phenobarbital …

Off-label use of antiepileptic drugs for the treatment of neonatal seizures

FS Silverstein, DM Ferriero - Pediatric neurology, 2008 - Elsevier
Medically refractory neonatal seizures represent a major therapeutic challenge in neonatal
intensive care units. Conventional antiepileptic drugs demonstrate limited efficacy. Previous …