Genomic imprinting disorders: lessons on how genome, epigenome and environment interact
Genomic imprinting, the monoallelic and parent-of-origin-dependent expression of a subset
of genes, is required for normal development, and its disruption leads to human disease …
of genes, is required for normal development, and its disruption leads to human disease …
Genomic imprinting: the emergence of an epigenetic paradigm
AC Ferguson-Smith - Nature Reviews Genetics, 2011 - nature.com
The emerging awareness of the contribution of epigenetic processes to genome function in
health and disease is underpinned by decades of research in model systems. In particular …
health and disease is underpinned by decades of research in model systems. In particular …
Genomic imprinting: parental influence on the genome
Genomic imprinting affects several dozen mammalian genes and results in the expression of
those genes from only one of the two parental chromosomes. This is brought about by …
those genes from only one of the two parental chromosomes. This is brought about by …
The discovery and importance of genomic imprinting
AC Ferguson-Smith, D Bourc'his - Elife, 2018 - elifesciences.org
The discovery of genomic imprinting by Davor Solter, Azim Surani and co-workers in the mid-
1980s has provided a foundation for the study of epigenetic inheritance and the epigenetic …
1980s has provided a foundation for the study of epigenetic inheritance and the epigenetic …
The role of genomic imprinting in biology and disease: an expanding view
J Peters - Nature Reviews Genetics, 2014 - nature.com
Genomic imprinting is an epigenetic phenomenon that results in monoallelic gene
expression according to parental origin. It has long been established that imprinted genes …
expression according to parental origin. It has long been established that imprinted genes …
Genomic imprinting mechanisms in mammals
FY Ideraabdullah, S Vigneau, MS Bartolomei - … Research/Fundamental and …, 2008 - Elsevier
Genomic imprinting is a form of epigenetic gene regulation that results in expression from a
single allele in a parent-of-origin-dependent manner. This form of monoallelic expression …
single allele in a parent-of-origin-dependent manner. This form of monoallelic expression …
What good is genomic imprinting: the function of parent-specific gene expression
JF Wilkins, D Haig - Nature Reviews Genetics, 2003 - nature.com
Parent-specific gene expression (genomic imprinting) is an evolutionary puzzle because it
forgoes an important advantage of diploidy—protection against the effects of deleterious …
forgoes an important advantage of diploidy—protection against the effects of deleterious …
[HTML][HTML] The role of imprinted genes in humans
M Ishida, GE Moore - Molecular aspects of medicine, 2013 - Elsevier
Genomic imprinting, a process of epigenetic modification which allows the gene to be
expressed in a parent-of-origin specific manner, has an essential role in normal growth and …
expressed in a parent-of-origin specific manner, has an essential role in normal growth and …
Genetic conflict reflected in tissue-specific maps of genomic imprinting in human and mouse
Genomic imprinting is an epigenetic process that restricts gene expression to either the
maternally or paternally inherited allele,. Many theories have been proposed to explain its …
maternally or paternally inherited allele,. Many theories have been proposed to explain its …
Mechanisms of genomic imprinting
K Pfeifer - The American Journal of Human Genetics, 2000 - cell.com
Imprinted genes represent a curious defiance of normal Mendelian genetics. Mammals
inherit two complete sets of chromosomes, one from the mother and one from the father, and …
inherit two complete sets of chromosomes, one from the mother and one from the father, and …
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