Genomic imprinting disorders: lessons on how genome, epigenome and environment interact

D Monk, DJG Mackay, T Eggermann, ER Maher… - Nature Reviews …, 2019 - nature.com
Genomic imprinting, the monoallelic and parent-of-origin-dependent expression of a subset
of genes, is required for normal development, and its disruption leads to human disease …

Genomic imprinting: the emergence of an epigenetic paradigm

AC Ferguson-Smith - Nature Reviews Genetics, 2011 - nature.com
The emerging awareness of the contribution of epigenetic processes to genome function in
health and disease is underpinned by decades of research in model systems. In particular …

Genomic imprinting: parental influence on the genome

W Reik, J Walter - Nature Reviews Genetics, 2001 - nature.com
Genomic imprinting affects several dozen mammalian genes and results in the expression of
those genes from only one of the two parental chromosomes. This is brought about by …

The discovery and importance of genomic imprinting

AC Ferguson-Smith, D Bourc'his - Elife, 2018 - elifesciences.org
The discovery of genomic imprinting by Davor Solter, Azim Surani and co-workers in the mid-
1980s has provided a foundation for the study of epigenetic inheritance and the epigenetic …

The role of genomic imprinting in biology and disease: an expanding view

J Peters - Nature Reviews Genetics, 2014 - nature.com
Genomic imprinting is an epigenetic phenomenon that results in monoallelic gene
expression according to parental origin. It has long been established that imprinted genes …

Genomic imprinting mechanisms in mammals

FY Ideraabdullah, S Vigneau, MS Bartolomei - … Research/Fundamental and …, 2008 - Elsevier
Genomic imprinting is a form of epigenetic gene regulation that results in expression from a
single allele in a parent-of-origin-dependent manner. This form of monoallelic expression …

What good is genomic imprinting: the function of parent-specific gene expression

JF Wilkins, D Haig - Nature Reviews Genetics, 2003 - nature.com
Parent-specific gene expression (genomic imprinting) is an evolutionary puzzle because it
forgoes an important advantage of diploidy—protection against the effects of deleterious …

[HTML][HTML] The role of imprinted genes in humans

M Ishida, GE Moore - Molecular aspects of medicine, 2013 - Elsevier
Genomic imprinting, a process of epigenetic modification which allows the gene to be
expressed in a parent-of-origin specific manner, has an essential role in normal growth and …

Genetic conflict reflected in tissue-specific maps of genomic imprinting in human and mouse

T Babak, B DeVeale, EK Tsang, Y Zhou, X Li… - Nature …, 2015 - nature.com
Genomic imprinting is an epigenetic process that restricts gene expression to either the
maternally or paternally inherited allele,. Many theories have been proposed to explain its …

Mechanisms of genomic imprinting

K Pfeifer - The American Journal of Human Genetics, 2000 - cell.com
Imprinted genes represent a curious defiance of normal Mendelian genetics. Mammals
inherit two complete sets of chromosomes, one from the mother and one from the father, and …