Flap endonuclease 1 (FEN1), an endogenous nuclease with the ability to cleave the 5′
overhang of branched dsDNA, is of significance in DNA replication and repair. The …

Flap endonuclease 1 (FEN1) is a structure-specific nuclease that cleaves the 5′ single-
stranded protrusion (also known as 5′ flap) during Okazaki fragment processing. It is …

Abstract Flap endonuclease 1 (FEN1), a ubiquitous enzyme involved in DNA repair and
replication, is overexpressed in highly proliferative cancer cells. FEN1 has been recognized …

Sensitive and accurate detection of flap endonuclease 1 (FEN1) is essential to understand
its roles in DNA replication and repair and explore its functions in tumor diagnosis and …

Abstract Flap endonuclease 1 (FEN1) is a nuclease overexpressed in cells with a high
replicate rate, which has been recognized as a potential biomarker in the molecular …

Flap endonuclease 1 (FEN1) participates in both DNA replication and repair to maintain the
stability and integrity of the genome. As a potential tumor marker, detecting FEN1 activity …

Flap endonuclease 1 (FEN1) becomes a potential tumor marker since it is closely related to
cancer occurrence and development. Here, a poly dA20-mediated nanoprobe (AuNPs-poly …

Flap structure-specific endonuclease 1 (FEN1) is overexpressed in various types of human
cancer cells and has been recognized as a promising biomarker for cancer diagnosis in the …

Abstract Flap endonuclease 1 (FEN1) is a structure-specific nuclease, which catalyzes the
removal of 5′ overhanging DNA flap from a specific DNA structure. FEN1 has been …

FEN1, a key participant in DNA replication and repair, is the major human flap
endonuclease that recognizes and cleaves flap DNA structures. Deficiencies in FEN1 …