DNA methylation is one of the epigenetic changes, which plays a major role in regulating
gene expression and, thus, many biological processes and diseases. There are several …

DNA methylation is an important mode of epigenetic modification and has great significance
in biochemistry, medicine and genomics. The development of techniques for DNA …

DNA methylation provides a pivotal layer of epigenetic regulation in eukaryotes that has
significant involvement for numerous biological processes in health and disease. The …

Cytosine methylation is an epigenetic mark that has a significant impact on the regulation of
transcription and replication of DNA. DNA methylation patterns are highly conserved across …

DNA methylation is the best-studied epigenetic modification and describes the conversion of
cytosine to 5-methylcytosine. The importance of this phenomenon is that aberrant promoter …

DNA methylation is the most studied epigenetic modification, and altered DNA methylation
patterns have been identified in cancer and more recently also in many other complex …

DNA methylation is a major form of epigenetic modification and plays essential roles in
physiology and disease processes. In the human genome, about 80% of cytosines in the 56 …

Motivation: Methylation of cytosines in DNA plays an important role in the regulation of gene
expression, and the analysis of methylation patterns is fundamental for the understanding of …

DNA methylation plays a critical role in the regulation of gene expression. The ability to
access the methylation status for a large number of genes or the entire genome should …

In the burgeoning field of epigenetics, there are several methods available to determine the
methylation status of DNA samples. However, choosing the method that is best suited to …