The aim of the present review paper is to survey the literature related to DNA methylation,
and its association with cancer and ageing. The review will outline the key factors, including …

Cancer and aging are two coupled developmental processes as reflected by the higher
incidence of cancer in the elderly human population group. Genetic mutations accumulate in …

DNA methylation is a heritable epigenetic feature that is associated with transcriptional
silencing, X-chromosome inactivation, genetic imprinting, and genomic stability. The …

DNA methylation is known to be abnormal in all forms of cancer, but it is not really
understood how this occurs and what is its role in tumorigenesis. In this review, we take a …

Over the past decades, DNA methylation has been proposed as a molecular mechanism
underlying the positive or negative effects of diet on human health. Despite the number of …

The biochemistry of aging is complex, with biologically significant changes occurring in
proteins, lipids and nucleic acids. One of these changes is in the methylation of DNA. DNA …

Epigenetic changes are inherited alterations in DNA that affect gene expression and
function without altering the DNA sequence. DNA methylation is one epigenetic process …

DNA methylation plays an essential role in maintaining cellular function, and changes in
methylation patterns may contribute to the development of autoimmunity, aging and cancer …

Aging is a major risk factor for individuals' health problems. Moreover, environmental signals
have a widespread influence on the aging process. Epigenetic modification, eg DNA …

It is well established that genotype plays an important role in the ageing process. However,
recent studies have suggested that epigenetic mechanisms may also influence the onset of …