Adipocytes are critical for ovarian cancer cells to home to the omentum, but the metabolic
changes initiated by this interaction are unknown. To this end, we carried out unbiased mass …

The standard treatment for high-grade serous ovarian cancer is primary debulking surgery
followed by chemotherapy. The extent of metastasis and invasive potential of lesions can …

Prostate cancer (PCa) is defined by dysregulated lipid signaling and is characterized by
upregulation of lipid metabolism-related genes including fatty acid binding protein 5 …

Intra-abdominal tumors, such as ovarian cancer,, have a clear predilection for metastasis to
the omentum, an organ primarily composed of adipocytes. Currently, it is unclear why tumor …

The increasing prevalence of obesity worldwide is associated with an increased risk of
various diseases, including multiple metabolic diseases, cardiovascular diseases, and …

Background The prognosis of colon cancer is poor for metastasis, while the mechanism,
especially adipocytes related, is not yet clear. The purpose of this study is to determine the …

The adipose tissue microenvironment plays a key role in tumour initiation and progression
because it provides fatty acids and adipokines to tumour cells. The fatty acid-binding protein …

Fatty acid-binding proteins (FABPs) are involved in binding and storing hydrophobic ligands
such as long-chain fatty acids, as well as transporting them to the appropriate compartments …

Early stage localized prostate cancer (PCa) has an excellent prognosis; however, patient
survival drops dramatically when PCa metastasizes. The molecular mechanisms underlying …

Epidemiologic studies have found that obesity is associated with malignant grade and
mortality in prostate cancer. Several adipokines have been implicated as putative mediating …