[HTML][HTML] The abdominal aortic aneurysm and intraluminal thrombus: current concepts of development and treatment

A Piechota-Polanczyk, A Jozkowicz… - Frontiers in …, 2015 - frontiersin.org
The pathogenesis of the abdominal aortic aneurysm (AAA) shows several hallmarks of
atherosclerotic and atherothrombotic disease, but comprises an additional, predominant …

Novel aspects of the pathogenesis of aneurysms of the abdominal aorta in humans

JB Michel, JL Martin-Ventura, J Egido… - Cardiovascular …, 2011 - academic.oup.com
Aneurysm of the abdominal aorta (AAA) is a particular, specifically localized form of
atherothrombosis, providing a unique human model of this disease. The pathogenesis of …

[HTML][HTML] Intraluminal thrombus: Innocent bystander or factor in abdominal aortic aneurysm pathogenesis?

AJ Boyd - JVS-Vascular Science, 2021 - Elsevier
Abstract Background Abdominal aortic aneurysms (AAAs) represent a complex multifactorial
hemodynamic, thrombotic, and inflammatory process that can ultimately result in aortic …

Role of oxidative stress in the pathogenesis of abdominal aortic aneurysms

ML McCormick, D Gavrila… - … , thrombosis, and vascular …, 2007 - Am Heart Assoc
The role of inflammation in the pathogenesis of abdominal aortic aneurysms (AAA) is well
established. The inflammatory process leads to protease-mediated degradation of the …

Mechanisms of abdominal aortic aneurysm formation

A Daugherty, LA Cassis - Current atherosclerosis reports, 2002 - Springer
Abdominal aortic aneurysms (AAA) are permanent dilations in the infra-renal area in which
the arterial tissue is characterized by inflammation and medial degeneration. AAAs are a …

Mechanisms of abdominal aortic aneurysm progression: A review

JP Gao, W Guo - Vascular Medicine, 2022 - journals.sagepub.com
Abdominal aortic aneurysm (AAA) is a common disease associated with significant
cardiovascular morbidity and mortality. Up to now, there is still controversy on the choice of …

Endothelium as a potential target for treatment of abdominal aortic aneurysm

J Sun, H Deng, Z Zhou, X Xiong… - Oxidative Medicine and …, 2018 - Wiley Online Library
Abdominal aortic aneurysm (AAA) was previously ascribed to weaken defective medial
arterial/adventitial layers, for example, smooth muscle/fibroblast cells. Therefore, besides …

Abdominal aortic aneurysms: fresh insights from a novel animal model of the disease

MW Manning, LA Cassis, J Huang… - Vascular …, 2002 - journals.sagepub.com
Abdominal aortic aneurysms (AAA) have a high prevalence in aged populations and are
responsible for a large number of deaths. Despite the widespread nature of the disease …

The role of endothelial dysfunction in aortic aneurysms

G Siasos, K Mourouzis, E Oikonomou… - Current …, 2015 - ingentaconnect.com
Abdominal aortic aneurysm is a vascular disease which, despite the fact that it shares
common risk factors with atherosclerosis, develops in parallel but as a partly independent …

Oxidative stress and abdominal aortic aneurysm: potential treatment targets

TI Emeto, JV Moxon, M Au, J Golledge - Clinical science, 2016 - portlandpress.com
Abdominal aortic aneurysm (AAA) is a significant cause of mortality in older adults. A key
mechanism implicated in AAA pathogenesis is inflammation and the associated production …