Antifungal resistance and new strategies to control fungal infections

P Vandeputte, S Ferrari… - International journal of …, 2012 - Wiley Online Library
Despite improvement of antifungal therapies over the last 30 years, the phenomenon of
antifungal resistance is still of major concern in clinical practice. In the last 10 years the …

Emerging new targets for the treatment of resistant fungal infections

N Liu, J Tu, G Dong, Y Wang… - Journal of medicinal …, 2018 - ACS Publications
With the increasing morbidity and mortality of invasive fungal infections and the emergence
of severe antifungal drug resistance, new drug targets and novel antifungal agents are …

Molecular mechanisms of acquired antifungal drug resistance in principal fungal pathogens and EUCAST guidance for their laboratory detection and clinical …

TR Rogers, PE Verweij, M Castanheira… - Journal of …, 2022 - academic.oup.com
The increasing incidence and changing epidemiology of invasive fungal infections continue
to present many challenges to their effective management. The repertoire of antifungal drugs …

Antifungal drug resistance: evolution, mechanisms and impact

NM Revie, KR Iyer, N Robbins, LE Cowen - Current opinion in …, 2018 - Elsevier
Highlights•Our limited arsenal of antifungals is threatened by drug-resistant fungal
pathogens.•Inherent resistance is when all strains of a species show antifungal …

Antifungal drug resistance: do molecular methods provide a way forward?

DS Perlin - Current Opinion in Infectious Diseases, 2009 - journals.lww.com
Antifungal drug resistance: do molecular methods provide a w... : Current Opinion in Infectious
Diseases Antifungal drug resistance: do molecular methods provide a way forward? : Current …

[HTML][HTML] Molecular evolution of antifungal drug resistance

N Robbins, T Caplan, LE Cowen - Annual review of …, 2017 - annualreviews.org
The fungal pathogens Candida albicans, Cryptococcus neoformans, and Aspergillus
fumigatus have transitioned from a rare curiosity to a leading cause of human mortality. The …

[HTML][HTML] Update on antifungal drug resistance

DS Perlin, E Shor, Y Zhao - Current clinical microbiology reports, 2015 - Springer
Invasive fungal infections remain a major source of global morbidity and mortality, especially
among patients with underlying immune suppression. Successful patient management …

Epigenetic mechanisms of drug resistance in fungi

Z Chang, V Yadav, SC Lee, J Heitman - Fungal Genetics and Biology, 2019 - Elsevier
The emergence of drug-resistant fungi poses a continuously increasing threat to human
health. Despite advances in preventive care and diagnostics, resistant fungi continue to …

A One Health approach to overcoming fungal disease and antifungal resistance

M Woods, JA McAlister… - WIREs Mechanisms of …, 2023 - Wiley Online Library
The global burden of fungal disease poses a substantial threat to human, animal, and
environmental health, endangering both human and livestock populations and creating …

[HTML][HTML] Tackling the emerging threat of antifungal resistance to human health

MC Fisher, A Alastruey-Izquierdo, J Berman… - Nature reviews …, 2022 - nature.com
Invasive fungal infections pose an important threat to public health and are an under-
recognized component of antimicrobial resistance, an emerging crisis worldwide. Across a …