Pharmacologic management of aneurysms
JH Lindeman, JS Matsumura - Circulation research, 2019 - Am Heart Assoc
Current management of aortic aneurysms relies exclusively on prophylactic operative repair
of larger aneurysms. Great potential exists for successful medical therapy that halts or …
of larger aneurysms. Great potential exists for successful medical therapy that halts or …
Pathogenic mechanisms and the potential of drug therapies for aortic aneurysm
B Liu, DJ Granville, J Golledge… - American Journal of …, 2020 - journals.physiology.org
Aortic aneurysm is a permanent focal dilation of the aorta. It is usually an asymptomatic
disease but can lead to sudden death due to aortic rupture. Aortic aneurysm-related …
disease but can lead to sudden death due to aortic rupture. Aortic aneurysm-related …
Therapies for thoracic aortic aneurysms and acute aortic dissections: old controversies and new opportunities
DM Milewicz, F Ramirez - Arteriosclerosis, Thrombosis, and …, 2019 - Am Heart Assoc
Thoracic aortic aneurysms that progress to acute aortic dissections are often fatal. Thoracic
aneurysms have been managed with treatment with β-adrenergic blocking agents (β …
aneurysms have been managed with treatment with β-adrenergic blocking agents (β …
Pathophysiology and therapeutics of thoracic aortic aneurysm in Marfan syndrome
K Asano, A Cantalupo, L Sedes, F Ramirez - Biomolecules, 2022 - mdpi.com
About 20% of individuals afflicted with thoracic aortic disease have single-gene mutations
that predispose the vessel to aneurysm formation and/or acute aortic dissection often without …
that predispose the vessel to aneurysm formation and/or acute aortic dissection often without …
[HTML][HTML] Effectiveness of combination of losartan potassium and doxycycline versus single-drug treatments in the secondary prevention of thoracic aortic aneurysm in …
HHC Yang, JM Kim, E Chum, C van Breemen… - The Journal of thoracic …, 2010 - Elsevier
OBJECTIVE: Losartan potassium (INN losartan), an antihypertensive drug, has been shown
to prevent thoracic aortic aneurysm in Marfan syndrome through the inhibition of …
to prevent thoracic aortic aneurysm in Marfan syndrome through the inhibition of …
Medical treatment of aortic aneurysms in Marfan syndrome and other heritable conditions
CHA Jost, M Greutmann, HM Connolly… - Current Cardiology …, 2014 - ingentaconnect.com
Thoracic aortic aneurysms can be triggered by genetic disorders such as Marfan syndrome
(MFS) and related aortic diseases as well as by inflammatory disorders such as giant cell …
(MFS) and related aortic diseases as well as by inflammatory disorders such as giant cell …
The mechanism and therapy of aortic aneurysms
Aortic aneurysm is a chronic aortic disease affected by many factors. Although it is generally
asymptomatic, it poses a significant threat to human life due to a high risk of rupture …
asymptomatic, it poses a significant threat to human life due to a high risk of rupture …
Update on clinical trials of losartan with and without β-blockers to block aneurysm growth in patients with Marfan syndrome: a review
MAH Bowman, KA Eagle, DM Milewicz - JAMA cardiology, 2019 - jamanetwork.com
Importance Thoracic aortic aneurysms leading to acute aortic dissections are a major cause
of morbidity and mortality despite significant advances in surgical treatment, which remains …
of morbidity and mortality despite significant advances in surgical treatment, which remains …
Basic science of abdominal aortic aneurysms: emerging therapeutic strategies for an unresolved clinical problem
RW Thompson - Current opinion in cardiology, 1996 - journals.lww.com
Abdominal aortic aneurysms (AAAs) are an increasingly common and potentially lethal
condition. Surgical repair of AAA is now yet performed quite safely, yet ruptured AAAs still …
condition. Surgical repair of AAA is now yet performed quite safely, yet ruptured AAAs still …
Novel mechanisms of abdominal aortic aneurysms
H Lu, DL Rateri, D Bruemmer, LA Cassis… - Current atherosclerosis …, 2012 - Springer
Abdominal aortic aneurysms (AAAs) are a common but asymptomatic disease that has high
susceptibility to rupture. Current therapeutic options are limited to surgical procedures …
susceptibility to rupture. Current therapeutic options are limited to surgical procedures …