Abstract Background DNA N6-methyldeoxyadenosine (6mA) is rarely present in mammalian
cells and its nuclear role remains elusive. Results Here we show that hypoxia induces …

The roles of RNA modification during organ metastasis of cancer cells are not known. Here
we established breast cancer lung metastasis cells by three rounds of selection of lung …

Abstract N6-methyladenosine (m 6 A) is a prevalent internal RNA modification in higher
eukaryotic cells. As the pivotal m 6 A regulator, RNA methyltransferase-like 3 (METTL3) is …

N 6-methyladenosine (m6A) is the most abundant epitranscriptome modification in
mammalian mRNA. Recent years have seen substantial progress in m6A epitranscriptomics …

Abstract N6-methyladenosine (m6A) RNA methylation and its associated methyltransferase
METTL3 play an important role in tumorigenesis of a series of tumors. However …

Summary N6-methyladenosine (m 6 A), one of the most prevalent RNA post-transcriptional
modifications, is involved in numerous biological processes. In previous studies, the …

Abstract In eukaryotes, N 6-methyladenosine (m6A) is the most prevalent epigenetic
alteration. Methyltransferase-like 3 (METTL3) is a key player in the control of m6A, although …

Abstract The methyltransferase like 3 (METTL3) has been generally recognized as a nuclear
protein bearing oncogenic properties. We find predominantly cytoplasmic METTL3 …

Abstract Background N6-methyladenosine (m6A) has emerged as a significant regulator of
the progress of various cancers. However, its role in lung adenocarcinoma (LUAD) remains …

Abstract Methyltransferase‑like 3 (METTL3) is an RNA methyltransferase that mediates
modification of N6‑methyladenosine (m6A), which serves as an oncogene in various types …