[HTML][HTML] Animal Models of Cryptococcus neoformans in Identifying Immune Parameters Associated With Primary Infection and Reactivation of Latent Infection

TG Normile, AM Bryan, M Del Poeta - Frontiers in Immunology, 2020 - frontiersin.org
Cryptococcus species are environmental fungal pathogens and the causative agents of
cryptococcosis. Infection occurs upon inhalation of infectious particles, which proliferate in …

[HTML][HTML] Adaptive immunology of Cryptococcus neoformans infections—an update

J Chen, J Shao, M Dai, W Fang, Y Yang - Frontiers in immunology, 2023 - frontiersin.org
The fungal genus Cryptococcus comprises a group of pathogens with considerable
phenotypic and genotypic diversity that can lead to cryptococcosis in both healthy and …

[HTML][HTML] Insights into the Mechanisms of Protective Immunity against Cryptococcus neoformans Infection Using a Mouse Model of Pulmonary Cryptococcosis

KL Wozniak, S Ravi, S Macias, ML Young… - PloS one, 2009 - journals.plos.org
Cryptococcus neoformans is an opportunistic fungal pathogen that causes life-threatening
pneumonia and meningoencephalitis in immune compromised individuals. Previous studies …

Cytokine and chemokine expression in the central nervous system associated with protective cell-mediated immunity against Cryptococcus neoformans

WC Uicker, HA Doyle, JP McCracken… - Medical …, 2005 - academic.oup.com
Cryptococcus neoformans is a yeast that causes cryptococcosis, a life-threatening disease
that develops following inhalation and dissemination of the organisms. C. neoformans has a …

Innate host defenses against Cryptococcus neoformans

C Hole, FL Wormley - Journal of Microbiology, 2016 - Springer
Cryptococcus neoformans, the predominant etiological agent of cryptococcosis, can cause
life-threatening infections of the central nervous system in immunocompromised and …

Immune response and immunotherapy to Cryptococcus infections

Q Zhou, WJ Murphy - Immunologic research, 2006 - Springer
Cryptococcus neoformans is a ubiquitous fungus that can cause lifethreatening infections
during immunosuppressive states such as acquired immunodeficiency syndrome (AIDS) …

[HTML][HTML] Induction of protective immunity against cryptococcosis

KL Wozniak, S Hardison, M Olszewski, FL Wormley - Mycopathologia, 2012 - Springer
Cryptococcus neoformans, the predominant etiological agent of cryptococcosis, is an
encapsulated fungal pathogen that can cause life-threatening infections of the central …

Cryptococcal interactions with the host immune system

K Voelz, RC May - Eukaryotic cell, 2010 - Am Soc Microbiol
Opportunistic pathogens have become of increasing medical importance over the last
decade due to the AIDS pandemic. Not only is cryptococcosis the fourth-most-common fatal …

Towards a vaccine for Cryptococcus neoformans: principles and caveats

K Datta, L Pirofski - FEMS yeast research, 2006 - academic.oup.com
In the Damage-response framework of microbial pathogenesis, infectious diseases are one
outcome of a host-microorganism interaction in a susceptible host. In cryptococcal disease …

[HTML][HTML] Use of Clinical Isolates to Establish Criteria for a Mouse Model of Latent Cryptococcus neoformans Infection

M Ding, KD Smith, DL Wiesner, JN Nielsen… - Frontiers in Cellular …, 2022 - frontiersin.org
The mechanisms of latency in the context of C. neoformans infection remain poorly
understood. Two reasons for this gap in knowledge are: 1) the lack of standardized criteria …