Glioblastoma multiforme (GBM), designated as World Health Organization (WHO) grade IV
astrocytoma, is a lethal and therapy-resistant brain cancer comprised of several tumor cell …

Glioblastoma Multiforme (GBM) is a grade IV astrocytoma, with a median survival of 14.6 mo.
Within GBM, stem-like cells, namely glioblastoma stem cells (GSCs), have the ability to self …

The discovery of glioblastoma stem cells (GSCs) in the 2000s revolutionized the cancer
research field, raising new questions regarding the putative cell (s) of origin of this tumor …

Glioblastoma is the most common, aggressive and lethal brain tumor in adults. However,
current therapeutic protocols have low success rates and average overall survival is less …

Glioblastoma multiforme (GBM) is the most common primary brain tumor and is notorious for
its poor prognosis. The highly invasive nature of GBM and its inherent resistance to therapy …

Background: Glioblastoma multiforme (GBM) continues to devastate patients and outfox
investigators and clinicians despite the preponderance of research directed at its biology …

Glioblastomas (GBMs) are highly lethal primary brain tumors. Despite current therapeutic
advances in other solid cancers, the treatment of these malignant gliomas remains …

Glioma stem cells (GSCs) constitute a slow-dividing, small population within a
heterogeneous glioblastoma. They are able to self-renew, recapitulate a whole tumor, and …

Glioblastoma multiforme (GBM) is a primary brain tumor with a high mortality rate and a
median survival time of~ 14 months from the initial diagnosis. Although progress has been …

Emerging evidence shows that glioblastoma multiforme (GBM) originates from cancer stem
cells (CSC s). Characterization of CSC‐specific signalling pathways would help identify new …