In spite of intense interest in how altered epigenetic processes including DNA methylation
may contribute to psychiatric and neurodevelopmental disorders, there is a limited …

Recent observations suggest that DNA methylation plays an important role in memory and
long-term potentiation (LTP) in the hippocampus and is involved in programming the …

ABSTRACT DNA methylation (DNAm) is a key epigenetic regulator of gene expression
across development. The developing prenatal brain is a highly dynamic tissue, but our …

To explore the role of DNA methylation in the brain, we examined the expression pattern of
de novo DNA methyltransferases Dnmt3a and Dnmt3b in the mouse central nervous system …

ABSTRACT DNA methylation is dynamically modulated during postnatal brain development,
and plays a key role in neuronal lineage commitment. This epigenetic mark has also …

DNA methylation is an epigenetic mechanism in which the methyl group is covalently
coupled to the C5 position of the cytosine residue of CpG dinucleotides. DNA methylation …

DNA methylation is a critical regulatory mechanism implicated in development, learning,
memory, and disease in the human brain. Here we have elucidated DNA methylation …

Background Tissues and their component cells have unique DNA methylation profiles
comprising DNA methylation patterns of tissue-dependent and differentially methylated …

Parent-specific differentially methylated regions (DMRs) are established during
gametogenesis and regulate parent-specific expression of imprinted genes. Monoallelic …

DNA methylation is an epigenetic regulatory mechanism commonly associated with
transcriptional silencing. DNA methyltransferases (DNMTs) are a family of related proteins …