The chemotactic cytokine fractalkine (FKN, chemokine CX3CL1) has unique properties
resulting from the combination of chemoattractants and adhesion molecules. The soluble …

Fractalkine/CX3CL1, the only member of the CX3C chemokine family, exists as a membrane‐
anchored molecule as well as in soluble form, each mediating different biological activities. It …

Inflammatory and immune responses are generated locally by the selective invasion and
accumulation of the immune cells into the lesion site. The infiltration process of the immune …

CX3CL1 is one of the 50 up-to-date identified and characterized chemokines. While other
chemokines are produced as small, secreted proteins, CX3CL1 (fractalkine) is synthetized …

Chemokine (C-X3-C motif) ligand 1 (CX3CL1, also known as fractalkine) and its receptor
chemokine (C-X3-C motif) receptor 1 (CX3CR1) are widely expressed in immune cells and …

Fractalkine (FKN) is a membrane-bound chemokine that can be released by proteolysis to
produce soluble FKN (s-FKN). FKN and its receptor, CX3CR1, are believed to be important …

Fractalkine (now also called CX3CL1) is a unique chemokine that functions not only as a
chemoattractant but also as an adhesion molecule and is expressed on endothelial cells …

A better understanding of the immunological processes governed by cytokines and
chemokines has shaped our approach to the design of therapeutics for diseases such as …

Fractalkine (also known as CX3CL1), a CX3C chemokine, activates and attracts monocytes/
macrophages to the site of injury/inflammation. It binds to CX3C receptor 1 (CX3CR1), a …

Fractalkine/CX3C chemokine ligand 1 (CX3CL1) is a chemokine involved in the anticancer
function of lymphocytes—mainly NK cells, T cells and dendritic cells. Its increased levels in …