Epigenetic transgenerational actions of vinclozolin on promoter regions of the sperm epigenome

C Guerrero-Bosagna, M Settles, B Lucker, MK Skinner - PloS one, 2010 - journals.plos.org
Previous observations have demonstrated that embryonic exposure to the endocrine
disruptor vinclozolin during gonadal sex determination promotes transgenerational adult …

Generational comparisons (F1 versus F3) of vinclozolin induced epigenetic transgenerational inheritance of sperm differential DNA methylation regions (epimutations) …

D Beck, I Sadler-Riggleman… - Environmental …, 2017 - academic.oup.com
Environmentally induced epigenetic transgenerational inheritance of disease and
phenotypic variation has been shown to involve DNA methylation alterations in the germline …

Epigenetic transgenerational inheritance of vinclozolin induced mouse adult onset disease and associated sperm epigenome biomarkers

C Guerrero-Bosagna, TR Covert, MM Haque… - Reproductive …, 2012 - Elsevier
The endocrine disruptor vinclozolin has previously been shown to promote epigenetic
transgenerational inheritance of adult onset disease in the rat. The current study was …

Alterations in sperm DNA methylation, non-coding RNA expression, and histone retention mediate vinclozolin-induced epigenetic transgenerational inheritance of …

M Ben Maamar, I Sadler-Riggleman… - Environmental …, 2018 - academic.oup.com
Epigenetic transgenerational inheritance of disease and phenotypic variation can be
induced by several toxicants, such as vinclozolin. This phenomenon can involve DNA …

Transgenerational sperm DNA methylation epimutation developmental origins following ancestral vinclozolin exposure

MK Skinner, E Nilsson, I Sadler-Riggleman, D Beck… - Epigenetics, 2019 - Taylor & Francis
ABSTRACT A number of environmental factors from nutrition to toxicants have been shown
to promote the epigenetic transgenerational inheritance of disease and phenotypic variation …

Vinclozolin induced epigenetic transgenerational inheritance of pathologies and sperm epimutation biomarkers for specific diseases

E Nilsson, SE King, M McBirney, D Kubsad… - PloS one, 2018 - journals.plos.org
Exposure to vinclozolin has been shown to induce the epigenetic transgenerational
inheritance of increased susceptibility to disease, and to induce transgenerational changes …

[HTML][HTML] Transgenerational epigenetic programming of the embryonic testis transcriptome

MD Anway, SS Rekow, MK Skinner - Genomics, 2008 - Elsevier
Embryonic exposure to the endocrine disruptor vinclozolin during gonadal sex
determination appears to promote an epigenetic reprogramming of the male germ line that is …

Transgenerational epigenetic imprinting of the male germline by endocrine disruptor exposure during gonadal sex determination

HS Chang, MD Anway, SS Rekow, MK Skinner - Endocrinology, 2006 - academic.oup.com
Embryonic exposure to the endocrine disruptor vinclozolin at the time of gonadal sex
determination was previously found to promote transgenerational disease states. The …

Epigenetic programming of the germ line: effects of endocrine disruptors on the development of transgenerational disease

MD Anway, MK Skinner - Reproductive biomedicine online, 2008 - Elsevier
Epigenetic programming of the germ line occurs during embryonic development in a sex-
specific manner. The male germ line becomes imprinted following sex determination …

Environmentally induced transgenerational epigenetic reprogramming of primordial germ cells and the subsequent germ line

MK Skinner, CGBM Haque, E Nilsson, R Bhandari… - PloS one, 2013 - journals.plos.org
A number of environmental factors (eg toxicants) have been shown to promote the
epigenetic transgenerational inheritance of disease and phenotypic variation …