Genomic imprinting affects several dozen mammalian genes and results in the expression of
those genes from only one of the two parental chromosomes. This is brought about by …

Genomic imprinting, a process of epigenetic modification which allows the gene to be
expressed in a parent-of-origin specific manner, has an essential role in normal growth and …

Imprinted genes represent a curious defiance of normal Mendelian genetics. Mammals
inherit two complete sets of chromosomes, one from the mother and one from the father, and …

Mammals are diploid organisms that inherit a complete chromosome set from each parent.
The vast majority of genes are equally expressed from both parental chromosomes …

Genomic imprinting is an epigenetic phenomenon that results in monoallelic gene
expression according to parental origin. It has long been established that imprinted genes …

), came as quite a surprise and forced classical Mendelian genetics to undergo a number of
revisions. The discovery of imprinting also presents us with a genetic paradox: by silencing …

Genomic imprinting, the parent-of-origin-specific silencing of a small proportion of genes,
introduces a paradoxical vulnerability of hemizygosity into the diploid mammalian genome …

Genomic imprinting refers to the process whereby specific genes are differentially marked
during parental gametogenesis, resulting in the differential expression of these genes in the …

Parent-specific gene expression (genomic imprinting) is an evolutionary puzzle because it
forgoes an important advantage of diploidy—protection against the effects of deleterious …

Publisher Summary This chapter discusses the developmental aspects of the imprinting
process and the kinds of factors that might participate in the imprinting process. It discusses …