[HTML][HTML] Methylation of IRAK3 is a novel prognostic marker in hepatocellular carcinoma

CC Kuo, YL Shih, HY Su, MD Yan… - World journal of …, 2015 - ncbi.nlm.nih.gov
AIM: To examine the methylation levels of interleukin-1 receptor-associated kinase 3
(IRAK3) and GLOXD1 and their potential clinical applications in hepatocellular carcinoma …

Diagnostic and prognostic roles of IRAK1 in hepatocellular carcinoma tissues: an analysis of immunohistochemistry and RNA-sequencing data from the cancer …

Z Ye, L Gao, D Wen, Y He, Y Pang… - OncoTargets and …, 2017 - Taylor & Francis
Background IRAK1 has been repoted to play an essential role in the development of
multiple cancers. However, the clinical significance of IRAK1 in hepatocellular carcinoma …

Aberrant DNA methylation profile and frequent methylation of KLK10 and OXGR1 genes in hepatocellular carcinoma

CY Lu, SY Hsieh, YJ Lu, CS Wu… - Genes …, 2009 - Wiley Online Library
Investigating aberrant DNA methylation in the cancer genome may identify genes that play
an important role in tumor progression. In this study, we combined differential methylation …

[HTML][HTML] Promoter methylation and mRNA expression of DKK-3 and WIF-1 in hepatocellular carcinoma

Z Ding, YB Qian, LX Zhu, QR Xiong - World journal of …, 2009 - ncbi.nlm.nih.gov
AIM: To investigate the promoter methylation status and mRNA expression of DKK-3 and
WIF-1 gene in hepatocellular carcinoma (HCC). METHODS: DKK-3 and WIF-1 acted as Wnt …

Hypermethylation of the IRAK3-Activated MAPK Signaling Pathway to Promote the Development of Glioma

X Wu, Y Ouyang, B Wang, J Lin… - Cancer Management and …, 2020 - Taylor & Francis
Objective This study aimed to elucidate the molecular mechanism underlying the
involvement of abnormal DNA methylation in the development of glioma and identify …

Evaluation of INK4A promoter methylation using pyrosequencing and circulating cell-free DNA from patients with hepatocellular carcinoma

G Huang, JD Krocker, JL Kirk, SN Merwat… - Clinical Chemistry and …, 2014 - degruyter.com
Abstract Background: Hyper-methylation of CpG dinucleotides in the promoter region of
inhibitor of cyclin-dependent kinase 4A (INK4A) has been reported in 60%–80% of …

Prognostic value of Iroquois homeobox 1 methylation in non-small cell lung cancers

JY Lee, WK Lee, JY Park, DS Kim - Genes & genomics, 2020 - Springer
Background Non-small cell lung cancer (NSCLC) poses a great threat to human health.
DNA methylation abnormalities play a central role in the development and outcome of most …

[HTML][HTML] IL-10 promoter hypomethylation is associated with increased IL-10 expression and poor survival in hepatocellular carcinoma

X Zhang, M Lu, Y Xu, G He, Q Liu, J Zhu… - Translational Cancer …, 2019 - ncbi.nlm.nih.gov
Background Epigenetic alterations of tumor-associated genes contribute to the
pathogenesis of virtually all cancer types. We evaluated the methylation status of the …

DNA methylation profiling identifies EYA4 gene as a prognostic molecular marker in hepatocellular carcinoma

X Hou, JX Peng, XY Hao, JP Cai, LJ Liang… - Annals of surgical …, 2014 - Springer
Background DNA hypermethylation plays important roles in carcinogenesis by silencing key
genes. This study aims to identify pivotal genes in hepatocellular carcinoma (HCC) by DNA …

LINE-1 methylation level and patient prognosis in a database of 208 hepatocellular carcinomas

K Harada, Y Baba, T Ishimoto, A Chikamoto… - Annals of surgical …, 2015 - Springer
Background The level of long interspersed nucleotide element-1 (LINE-1) methylation has
become regarded as a surrogate marker of global DNA methylation. Previously, we …