The term “epigenetics” refers to modifications in gene expression caused by heritable, but
potentially reversible, changes in DNA methylation and chromatin structure. Given the fact …

The term “epigenetics” refers to modifications in gene expression caused by heritable, but
potentially reversible, changes in DNA methylation and chromatin structure. Epigenetic …

It is now appreciated that both genetic alteration, eg mutations, and aberrant epigenetic
changes, eg DNA methylation, cause cancer. Epigenetic dysregulation is potentially …

Epigenetic events, a key driving force in the development of cancer, are alterations in gene
expression without changes in the DNA coding sequence that are heritable through cell …

Studies during the last two decades have revealed the involvement of epigenetic
modifications in the development of human cancer. It is now recognized that the interplay of …

Cancer can take many years to develop from initiation to progression. The long period of
development might represent an opportunity to use multi-functional, multi-targeted …

Disruption of the epigenome has been a hallmark of human cancers and has been linked
with tumor pathogenesis and progression. Since epigenetic changes can be reversed in …

Epigenetics provides the key to transform the genetic information into phenotype and
because of its reversibility it is considered an ideal target for therapeutic interventions. This …

The influence of diet and environment on human health has been known since ages. Plant-
derived natural bioactive compounds (phytochemicals) have acquired an important role in …

The hallmarks of carcinogenesis are aberrations in gene expression and protein function
caused by both genetic and epigenetic modifications. Epigenetics refers to the changes in …