[HTML][HTML] Convection-enhanced delivery
AM Mehta, AM Sonabend, JN Bruce - Neurotherapeutics, 2017 - Elsevier
Convection-enhanced delivery (CED) is a promising technique that generates a pressure
gradient at the tip of an infusion catheter to deliver therapeutics directly through the …
gradient at the tip of an infusion catheter to deliver therapeutics directly through the …
Convection‐enhanced drug delivery to the brain: Therapeutic potential and neuropathological considerations
Convection‐enhanced delivery (CED) describes a direct method of drug delivery to the brain
through intraparenchymal microcatheters. By establishing a pressure gradient at the tip of …
through intraparenchymal microcatheters. By establishing a pressure gradient at the tip of …
[HTML][HTML] Chronic, intermittent convection-enhanced delivery devices
O Lewis, M Woolley, D Johnson, A Rosser… - Journal of neuroscience …, 2016 - Elsevier
Background Intraparenchymal convection-enhanced delivery (CED) of therapeutics directly
into the brain has long been endorsed as a medium through which meaningful …
into the brain has long been endorsed as a medium through which meaningful …
[HTML][HTML] Convection-enhanced delivery of therapeutics for brain disease, and its optimization
R Raghavan, ML Brady, MI Rodríguez-Ponce… - Neurosurgical …, 2006 - thejns.org
✓ Convection-enhanced delivery (CED) is the continuous injection under positive pressure
of a fluid containing a therapeutic agent. This technique was proposed and introduced by …
of a fluid containing a therapeutic agent. This technique was proposed and introduced by …
Convection-enhanced delivery to the central nervous system
RR Lonser, M Sarntinoranont, PF Morrison… - Journal of …, 2015 - thejns.org
Convection-enhanced delivery (CED) is a bulk flow–driven process. Its properties permit
direct, homogeneous, targeted perfusion of CNS regions with putative therapeutics while …
direct, homogeneous, targeted perfusion of CNS regions with putative therapeutics while …
Convection-enhanced delivery for the treatment of glioblastoma
MA Vogelbaum, MK Aghi - Neuro-oncology, 2015 - academic.oup.com
Effective treatment of glioblastoma (GBM) remains a formidable challenge. Survival rates
remain poor despite decades of clinical trials of conventional and novel, biologically …
remain poor despite decades of clinical trials of conventional and novel, biologically …
Convection-enhanced delivery for the treatment of brain tumors
W Debinski, SB Tatter - Expert review of neurotherapeutics, 2009 - Taylor & Francis
The brain is highly accessible for nutrients and oxygen, however delivery of drugs to
malignant brain tumors is a very challenging task. Convection-enhanced delivery (CED) has …
malignant brain tumors is a very challenging task. Convection-enhanced delivery (CED) has …
Image-guided convection-enhanced delivery platform in the treatment of neurological diseases
MS Fiandaca, JR Forsayeth, PJ Dickinson… - …, 2008 - Springer
Convection-enhanced delivery (CED) of substances within the human brain is becoming a
more frequent experimental treatment option in the management of brain tumors, and more …
more frequent experimental treatment option in the management of brain tumors, and more …
Future of convection-enhanced delivery in the treatment of brain tumors
DS Bidros, JK Liu, MA Vogelbaum - Future oncology, 2010 - Taylor & Francis
Gliomas are one of the most lethal forms of cancer. The poor prognosis associated with
these malignant primary brain tumors treated with surgery, radiotherapy and chemotherapy …
these malignant primary brain tumors treated with surgery, radiotherapy and chemotherapy …
[HTML][HTML] Convection-enhanced delivery: connection to and impact of interstitial fluid flow
CA Stine, JM Munson - Frontiers in oncology, 2019 - frontiersin.org
Convection-enhanced delivery (CED) is a method used to increase transport of therapeutics
in and around brain tumors. CED works through locally applying a pressure differential to …
in and around brain tumors. CED works through locally applying a pressure differential to …