Epigenetic changes by per-and polyfluoroalkyl substances (PFAS)

S Kim, I Thapar, BW Brooks - Environmental pollution, 2021 - Elsevier
Increasing studies are examining per-and polyfluoroalkyl substances (PFAS) induced
toxicity and resulting health outcomes, including epigenetic modifications (eg, DNA …

Blood transcriptomics analysis of fish exposed to perfluoro alkyls substances: assessment of a non-lethal sampling technique for advancing aquatic toxicology …

IA Rodríguez-Jorquera, RC Colli-Dula… - … science & technology, 2018 - ACS Publications
In contrast to mammals, the blood from other vertebrates such as fish contains nucleated red
cells. Using a fathead minnow (Pimephales promelas) oligonucleotide microarray, we …

8: 8 Perfluoroalkyl phosphinic acid affects neurobehavioral development, thyroid disruption, and DNA methylation in developing zebrafish

S Kim, KM Stroski, G Killeen, C Smitherman… - Science of the Total …, 2020 - Elsevier
Recent studies have reported potential neurotoxicity and epigenetic alteration associated
with exposure to several per-and polyfluoroalkyl substances (PFASs). However, such …

Gestational perfluoroalkyl substance exposure and DNA methylation at birth and 12 years of age: a longitudinal epigenome-wide association study

Y Liu, MN Eliot, GD Papandonatos… - Environmental …, 2022 - ehp.niehs.nih.gov
Background: DNA methylation alterations may underlie associations between gestational
perfluoroalkyl substances (PFAS) exposure and later-life health outcomes. To the best of our …

Health-related toxicity of emerging per-and polyfluoroalkyl substances: Comparison to legacy PFOS and PFOA

LJL Espartero, M Yamada, J Ford, G Owens… - Environmental …, 2022 - Elsevier
Per-and polyfluoroalkyl substances (PFAS) are highly persistent, manufactured chemicals
used in various manufacturing processes and found in numerous commercial products. With …

[HTML][HTML] Acute PFOA exposure promotes epigenomic alterations in mouse kidney tissues

F Rashid, A Ramakrishnan, C Fields, J Irudayaraj - Toxicology reports, 2020 - Elsevier
Perfluorooctanoic acid (PFOA), a manufactured perfluorochemical is a common surfactant
and environmental pollutant found in various consumer products and water sources …

Toward a mechanistic understanding of poly-and perfluoroalkylated substances and cancer

RI Boyd, S Ahmad, R Singh, Z Fazal, GS Prins… - Cancers, 2022 - mdpi.com
Simple Summary Poly-and perfluoroalkylated substances (PFAS) are industrial chemicals
found in many household products that persist in the environment. While several excellent …

Bioactivity profiling of per-and polyfluoroalkyl substances (PFAS) identifies potential toxicity pathways related to molecular structure

KA Houck, G Patlewicz, AM Richard, AJ Williams… - Toxicology, 2021 - Elsevier
Per-and polyfluoroalkyl substances (PFAS) are a broad class of hundreds of fluorinated
chemicals with environmental health concerns due to their widespread presence and …

Application of the key characteristics of carcinogens to per and polyfluoroalkyl substances

AM Temkin, BA Hocevar, DQ Andrews… - International journal of …, 2020 - mdpi.com
Per-and polyfluoroalkyl substances (PFAS) constitute a large class of environmentally
persistent chemicals used in industrial and consumer products. Human exposure to PFAS is …

A review of the pathways of human exposure to poly-and perfluoroalkyl substances (PFASs) and present understanding of health effects

EM Sunderland, XC Hu, C Dassuncao… - Journal of exposure …, 2019 - nature.com
Here, we review present understanding of sources and trends in human exposure to poly-
and perfluoroalkyl substances (PFASs) and epidemiologic evidence for impacts on cancer …