[HTML][HTML] C3 glomerulonephritis: clinicopathological findings, complement abnormalities, glomerular proteomic profile, treatment, and follow-up

S Sethi, FC Fervenza, Y Zhang, L Zand, JA Vrana… - Kidney international, 2012 - Elsevier
C3 glomerulonephritis (C3GN) is a recently described disorder that typically results from
abnormalities in the alternative pathway (AP) of complement. Here, we describe the clinical …

Clinical findings, pathology, and outcomes of C3GN after kidney transplantation

L Zand, EC Lorenz, FG Cosio… - Journal of the …, 2014 - journals.lww.com
Abstract C3 glomerulonephritis (C3GN) results from abnormalities in the alternative pathway
of complement, and it is characterized by deposition of C3 with absent or scant Ig deposition …

C3 glomerulonephritis associated with monoclonal gammopathy: a case series

L Zand, A Kattah, FC Fervenza, RJH Smith… - American journal of …, 2013 - Elsevier
Background C3 glomerulonephritis (GN) is a proliferative GN resulting from glomerular
deposition of complement factors due to dysregulation of the alternative pathway of …

Kidney transplantation in C3 glomerulopathy: a case series

R Regunathan-Shenk, RS Avasare, W Ahn… - American Journal of …, 2019 - Elsevier
Rationale & Objective C3 glomerulopathy (C3G), a form of glomerulonephritis associated
with dysregulation of the alternative complement pathway, occurs either as dense deposit …

Update on C3 glomerulopathy: a complement-mediated disease

F Caravaca-Fontán, L Lucientes, T Cavero, M Praga - Nephron, 2020 - karger.com
Abstract C3 glomerulopathy (C3G) is a clinicopathologic entity secondary to dysregulation of
the alternative complement pathway in plasma and the glomerular microenvironment. The …

C3 Glomerulopathy

M Riedl, P Thorner, C Licht - Pediatric Nephrology, 2017 - Springer
Recent advances in our understanding of the disease pathology of membranoproliferative
glomerulonephritis has resulted in its re-classification as complement C3 glomerulopathy …

[HTML][HTML] C3 glomerulopathy: consensus report

MC Pickering, VD D'agati, CM Nester, RJ Smith… - Kidney international, 2013 - Elsevier
C3 glomerulopathy is a recently introduced pathological entity whose original definition was
glomerular pathology characterized by C3 accumulation with absent or scanty …

C3 glomerulopathy—understanding a rare complement-driven renal disease

RJH Smith, GB Appel, AM Blom, HT Cook… - Nature reviews …, 2019 - nature.com
The C3 glomerulopathies are a group of rare kidney diseases characterized by complement
dysregulation occurring in the fluid phase and in the glomerular microenvironment, which …

C3 glomerulopathy: ten years' experience at Mayo Clinic

A Ravindran, FC Fervenza, RJH Smith… - Mayo Clinic …, 2018 - Elsevier
Objective To describe the clinicopathological features, complement abnormalities, triggers,
treatment, and outcomes of C3 glomerulopathy. Patients and Methods A total of 114 patients …

[HTML][HTML] C3 glomerulonephritis and dense deposit disease share a similar disease course in a large United States cohort of patients with C3 glomerulopathy

AS Bomback, D Santoriello, RS Avasare… - Kidney international, 2018 - Elsevier
C3 glomerulonephritis (C3GN) and dense deposit disease comprise the two classes of C3
glomerulopathy. Studies from Europe and Asia have aided our understanding of this …