Breast cancer (BC) is the most prevalent cancer in women worldwide. Although extensive
studies are ongoing concerning its intricate molecular mechanisms, development of novel …

The methylation of promoter CpG islands and the interaction between microRNAs (miRNAs)
and messenger RNAs (mRNAs) of target genes are considered two crucial mechanisms for …

Breast cancer is the most prevalent cancer in the world. Currently, the main treatments for
breast cancer are radiotherapy, chemotherapy, targeted therapy and surgery. The treatment …

MicroRNAs (miRNAs) are shown to regulate various processes in cancer like motility and
invasion that are key features of the metastatic triple negative breast cancer (TNBCs) …

miRNAs are important regulators of gene expression that are frequently deregulated in
cancer, with aberrant DNA methylation being an epigenetic mechanism involved in this …

miRNAs are some of the most well-characterized regulators of gene expression. Integral to
several physiological processes, their aberrant expression often drives the pathogenesis of …

DNA methylation plays a key role in the silencing of numerous cancer-related genes,
thereby affecting a number of vital cellular processes, including the cell cycle checkpoint …

Abstract Background miR-133a-3p has been recently discovered to be down-regulated in
various human malignancies, including breast cancer, and reduced miR-133a-3p levels …

Epigenetics refers to the heritable changes in gene expression without a change in the DNA
sequence itself. Two of these major changes include aberrant DNA methylation as well as …

ABSTRACT microRNAs (miRNAs) and DNA methylation are the 2 epigenetic modifications
that have emerged in recent years as the most critical players in the regulation of gene …