Characterization of tissue-specific differential DNA methylation suggests distinct modes of positive and negative gene expression regulation
Background DNA methylation plays an important role in regulating gene expression during
many biological processes. However, the mechanism of DNA-methylation-dependent gene …
many biological processes. However, the mechanism of DNA-methylation-dependent gene …
DNA methylation profile of tissue-dependent and differentially methylated regions (T-DMRs) in mouse promoter regions demonstrating tissue-specific gene expression
S Yagi, K Hirabayashi, S Sato, W Li… - Genome …, 2008 - genome.cshlp.org
DNA methylation constitutes an important epigenetic regulation mechanism in many
eukaryotes, although the extent of DNA methylation in the regulation of gene expression in …
eukaryotes, although the extent of DNA methylation in the regulation of gene expression in …
[HTML][HTML] On the presence and role of human gene-body DNA methylation
DNA methylation of promoter sequences is a repressive epigenetic mark that down-
regulates gene expression. However, DNA methylation is more prevalent within gene …
regulates gene expression. However, DNA methylation is more prevalent within gene …
Tissue-specific DNA methylation is conserved across human, mouse, and rat, and driven by primary sequence conservation
Background Uncovering mechanisms of epigenome evolution is an essential step towards
understanding the evolution of different cellular phenotypes. While studies have confirmed …
understanding the evolution of different cellular phenotypes. While studies have confirmed …
Emerging concept in DNA methylation: role of transcription factors in shaping DNA methylation patterns
DNA methylation in mammals is a key epigenetic modification essential to normal genome
regulation and development. DNA methylation patterns are established during early …
regulation and development. DNA methylation patterns are established during early …
Genome-wide quantification of the effects of DNA methylation on human gene regulation
Changes in DNA methylation are involved in development, disease, and the response to
environmental conditions. However, not all regulatory elements are functionally methylation …
environmental conditions. However, not all regulatory elements are functionally methylation …
Genome-wide survey reveals dynamic widespread tissue-specific changes in DNA methylation during development
Background Changes in DNA methylation in the mammalian genome during development
are frequent events and play major roles regulating gene expression and other …
are frequent events and play major roles regulating gene expression and other …
Genome-wide analysis reveals that exon methylation facilitates its selective usage in the human transcriptome
DNA methylation, especially in promoter regions, is a well-characterized epigenetic marker
related to gene expression regulation in eukaryotes. However, the role of intragenic DNA …
related to gene expression regulation in eukaryotes. However, the role of intragenic DNA …
Epigenetics: differential DNA methylation in mammalian somatic tissues
H Nagase, S Ghosh - The FEBS journal, 2008 - Wiley Online Library
Epigenetics refers to heritable phenotypic alterations in the absence of DNA sequence
changes, and DNA methylation is one of the extensively studied epigenetic alterations. DNA …
changes, and DNA methylation is one of the extensively studied epigenetic alterations. DNA …
Passive and active DNA methylation and the interplay with genetic variation in gene regulation
DNA methylation is an essential epigenetic mark whose role in gene regulation and its
dependency on genomic sequence and environment are not fully understood. In this study …
dependency on genomic sequence and environment are not fully understood. In this study …
相关搜索
- dna methylation gene regulation
- dna methylation transcription factors
- dna methylation sequence conservation
- quantification of the effects gene regulation
- dna methylation quantification of the effects
- dna methylation gene expression
- dna methylation gene body
- genetic variation gene regulation
- dna methylation genetic variation