Background: Melatonin is an indolic compound mainly secreted by the pineal gland and
plays a vital role in the regulation of circadian rhythms and cancer therapy. However, the …

Melatonin, which is synthesized by the pineal gland and released into the blood, exhibits
antitumor properties. However, the mechanisms underlying these effects, particularly in …

Background/Aims: Melatonin, synthesized by the pineal gland and released into the blood,
appears to have antitumour properties; however, the mechanisms of its anti-cancer effects …

Melatonin is synthesized by the pineal gland and is released into the blood. In the last
several years, some studies have shown that melatonin has anticancer properties; however …

Melatonin exhibits antitumour activities in the treatment of many human cancers. In the
present study, we aimed to improve the therapeutic potential of melatonin in gastric cancer …

Globally, gastric cancer (GC) is one of the most common types of cancer and the third
leading cause of cancer‑related death. In China, gastric and liver cancers have the highest …

We previously demonstrated that melatonin could be used as a chemopreventive agent for
inhibiting cholangiocarcinoma (CCA) development in a hamster model. However, the …

Although melatonin has been shown to exert marked antitumor effects against a variety of
cancers, the underlying mechanisms remain to be fully elucidated. It has been hypothesized …

The pineal hormone, melatonin (MLT), has been shown to have therapeutic effects in
patients with gastric cancer; however, the mechanisms for the anti-cancer effects are …

Background Ovarian cancer is a highly aggressive disease that is frequently diagnosed in
advanced stages. Melatonin, with its numerous antitumor properties, holds great promise in …