Sensorimotor representations in cerebellar granule cells in larval zebrafish are dense, spatially organized, and non-temporally patterned

LD Knogler, DA Markov, EI Dragomir, V Štih… - Current Biology, 2017 - cell.com
A fundamental question in neurobiology is how animals integrate external sensory
information from their environment with self-generated motor and sensory signals in order to …

Motor context dominates output from purkinje cell functional regions during reflexive visuomotor behaviours

LD Knogler, AM Kist, R Portugues - Elife, 2019 - elifesciences.org
The cerebellum integrates sensory stimuli and motor actions to enable smooth coordination
and motor learning. Here we harness the innate behavioral repertoire of the larval zebrafish …

Gene expression profiling of granule cells and Purkinje cells in the zebrafish cerebellum

M Takeuchi, S Yamaguchi, Y Sakakibara… - Journal of …, 2017 - Wiley Online Library
The structure of the neural circuitry of the cerebellum, which functions in some types of motor
learning and coordination, is generally conserved among vertebrates. However, some …

Cerebellar output in zebrafish: an analysis of spatial patterns and topography in eurydendroid cell projections

LA Heap, CC Goh, KS Kassahn… - Frontiers in Neural Circuits, 2013 - frontiersin.org
The cerebellum is a brain region responsible for motor coordination and for refining motor
programs. While a great deal is known about the structure and connectivity of the …

Brain-wide organization of neuronal activity and convergent sensorimotor transformations in larval zebrafish

X Chen, Y Mu, Y Hu, AT Kuan, M Nikitchenko… - Neuron, 2018 - cell.com
Simultaneous recordings of large populations of neurons in behaving animals allow detailed
observation of high-dimensional, complex brain activity. However, experimental approaches …

Multimodal integration in granule cells as a basis for associative plasticity and sensory prediction in a cerebellum-like circuit

NB Sawtell - Neuron, 2010 - cell.com
The recoding of diverse sensory and motor signals by granule cells (GCs) is probably critical
for the function of cerebellar circuits, yet the nature of these transformations and their …

Cerebellar-dependent learning in larval zebrafish

M Aizenberg, EM Schuman - Journal of Neuroscience, 2011 - Soc Neuroscience
Understanding how neuronal network activity contributes to memory formation is challenged
by the complexity of most brain circuits and the restricted ability to monitor the activity of …

The cellular organization of zebrafish visuomotor circuits

MB Orger - Current Biology, 2016 - cell.com
Week-old zebrafish execute many complex, visually guided actions using a brain that
displays the canonical vertebrate organization, but is less than a cubic millimeter in size …

Functional regionalization of the teleost cerebellum analyzed in vivo

H Matsui, K Namikawa, A Babaryka… - Proceedings of the …, 2014 - National Acad Sciences
There has been accumulating evidence for a regionalized organization of the cerebellum,
which was mostly deduced from anatomical mapping of axonal projections of cerebellar …

Predictive neural computations in the cerebellum contribute to motor planning and faster behavioral responses in larval zebrafish

S Narayanan, A Varma, V Thirumalai - Science Advances, 2024 - science.org
The ability to predict the future based on past experience lies at the core of the brain's ability
to adapt behavior. However, the neural mechanisms that participate in generating and …