Gene expression profiling of brain samples from patients with Lewy body dementia
Abstract Dementia with Lewy Bodies (DLB) is the second most common neurodegenerative
disorder in the elderly. The development and progression of DLB remain unclear. In this …
disorder in the elderly. The development and progression of DLB remain unclear. In this …
Epigenetic regulation in the pathophysiology of Lewy body dementia
Lewy body dementia encompasses both dementia with Lewy bodies and Parkinson's
disease dementia. Although both are common causes of dementia, they remain relatively …
disease dementia. Although both are common causes of dementia, they remain relatively …
[HTML][HTML] Blood mRNA expression in Alzheimer's disease and dementia with Lewy bodies
Objectives The objective of this study was to investigate the expression of genes in
Alzheimer's disease (AD) and dementia with Lewy bodies (DLB), both at the mild cognitive …
Alzheimer's disease (AD) and dementia with Lewy bodies (DLB), both at the mild cognitive …
Systematic review of gene expression studies in people with Lewy body dementia
A Chowdhury, AP Rajkumar - Acta Neuropsychiatrica, 2020 - cambridge.org
Objectives: Lewy body dementia (LBD) is the second most prevalent neurodegenerative
dementia and it causes more morbidity and mortality than Alzheimer's disease. Several …
dementia and it causes more morbidity and mortality than Alzheimer's disease. Several …
Extracellular vesicle microRNA-mediated transcriptional regulation may contribute to dementia with Lewy bodies molecular pathology
FB Isik, HM Knight, AP Rajkumar - Acta neuropsychiatrica, 2024 - cambridge.org
Objective: Dementia with Lewy bodies (DLB) is the second most common dementia.
Advancing our limited understanding of its molecular pathogenesis is essential for …
Advancing our limited understanding of its molecular pathogenesis is essential for …
Cross-platform transcriptional profiling identifies common and distinct molecular pathologies in Lewy body diseases
R Feleke, RH Reynolds, AM Smith, B Tilley… - Acta …, 2021 - Springer
Abstract Parkinson's disease (PD), Parkinson's disease with dementia (PDD) and dementia
with Lewy bodies (DLB) are three clinically, genetically and neuropathologically overlapping …
with Lewy bodies (DLB) are three clinically, genetically and neuropathologically overlapping …
Transcriptional network analysis in frontal cortex in L ewy body diseases with focus on dementia with L ewy bodies
G Santpere, P Garcia‐Esparcia… - Brain …, 2018 - Wiley Online Library
The present study investigates global transcriptional changes in frontal cortex area 8 in
incidental Lewy Body disease (iLBD), Parkinson disease (PD) and Dementia with Lewy …
incidental Lewy Body disease (iLBD), Parkinson disease (PD) and Dementia with Lewy …
Next-generation RNA-sequencing of serum small extracellular vesicles discovers potential diagnostic biomarkers for dementia with Lewy bodies
AP Rajkumar, A Hye, J Lange, YR Manesh… - The American Journal of …, 2021 - Elsevier
Objective There is an urgent clinical need for identifying blood-based diagnostic biomarkers
for Dementia with Lewy Bodies (DLB). Transcriptomic studies have reported unique RNA …
for Dementia with Lewy Bodies (DLB). Transcriptomic studies have reported unique RNA …
[HTML][HTML] Elucidating distinct molecular signatures of Lewy body dementias
Dementia with Lewy bodies and Parkinson's disease dementia are common
neurodegenerative diseases that share similar neuropathological profiles and spectra of …
neurodegenerative diseases that share similar neuropathological profiles and spectra of …
CSF proteome profiling reveals biomarkers to discriminate dementia with Lewy bodies from Alzheimer s disease
M Del Campo, L Vermunt, CFW Peeters… - Nature …, 2023 - nature.com
Diagnosis of dementia with Lewy bodies (DLB) is challenging and specific biofluid
biomarkers are highly needed. We employed proximity extension-based assays to measure …
biomarkers are highly needed. We employed proximity extension-based assays to measure …