Human endogenous retrovirus K in cancer: a potential biomarker and immunotherapeutic target
G Curty, JL Marston, M de Mulder Rougvie, FE Leal… - Viruses, 2020 - mdpi.com
In diseases where epigenetic mechanisms are changed, such as cancer, many genes show
altered gene expression and inhibited genes become activated. Human endogenous …
altered gene expression and inhibited genes become activated. Human endogenous …
The role of HERV-K in cancer stemness
Human endogenous retrovirus-K (HERV-K) is the most recently integrated retrovirus in the
human genome, with implications for multiple disorders, including cancer. Although typically …
human genome, with implications for multiple disorders, including cancer. Although typically …
The role of endogenous retroviruses‐K in human cancer
Z Salavatiha, R Soleimani‐Jelodar… - Reviews in Medical …, 2020 - Wiley Online Library
It is known that human endogenous retroviruses (HERVs) constitute almost 8% of the human
genome. Although the expression of HERVs from the human genome is tightly regulated …
genome. Although the expression of HERVs from the human genome is tightly regulated …
Downregulation of Human Endogenous Retrovirus Type K (HERV-K) Viral env RNA in Pancreatic Cancer Cells Decreases Cell Proliferation and Tumor Growth
M Li, L Radvanyi, B Yin, K Rycaj, J Li, R Chivukula… - Clinical Cancer …, 2017 - AACR
Purpose: We investigated the role of the human endogenous retrovirus type K (HERV-K)
envelope (env) gene in pancreatic cancer. Experimental Design: shRNA was employed to …
envelope (env) gene in pancreatic cancer. Experimental Design: shRNA was employed to …
[HTML][HTML] Human endogenous retroviruses and cancer
M Gonzalez-Cao, P Iduma, N Karachaliou… - Cancer biology & …, 2016 - ncbi.nlm.nih.gov
Human endogenous retroviruses (HERVs) are retroviruses that infected human genome
millions of years ago and have persisted throughout human evolution. About 8% of our …
millions of years ago and have persisted throughout human evolution. About 8% of our …
Human endogenous retrovirus K and cancer: Innocent bystander or tumorigenic accomplice?
RF Downey, FJ Sullivan… - … Journal of Cancer, 2015 - Wiley Online Library
Harbored as relics of ancient germline infections, human endogenous retroviruses (HERVs)
now constitute up to 8% of our genome. A proportion of this sequence has been co‐opted for …
now constitute up to 8% of our genome. A proportion of this sequence has been co‐opted for …
Anti-HERV-K drugs and vaccines, possible therapies against tumors
S Hosseiniporgham, LA Sechi - Vaccines, 2023 - mdpi.com
The footprint of human endogenous retroviruses (HERV), specifically HERV-K, has been
found in malignancies, such as melanoma, teratocarcinoma, osteosarcoma, breast cancer …
found in malignancies, such as melanoma, teratocarcinoma, osteosarcoma, breast cancer …
Human endogenous retrovirus K triggers an antigen-specific immune response in breast cancer patients
F Wang-Johanning, L Radvanyi, K Rycaj, JB Plummer… - Cancer research, 2008 - AACR
Recent evidence indicates that human cancer cells reactivate the expression of latent
human endogenous retroviral (HERV) proteins. However, the extent to which cancer …
human endogenous retroviral (HERV) proteins. However, the extent to which cancer …
Detection of human endogenous retrovirus K (HERV-K) transcripts in human prostate cancer cell lines
L Agoni, C Guha, J Lenz - Frontiers in oncology, 2013 - frontiersin.org
Human endogenous retroviruses (HERVs) are transcribed in many cancers including
prostate cancer. Human endogenous retrovirus K (HERV-K) of the HML2 subtype is the most …
prostate cancer. Human endogenous retrovirus K (HERV-K) of the HML2 subtype is the most …
Human endogenous retrovirus K (HML-2) in health and disease
B Xue, LA Sechi, DJ Kelvin - Frontiers in microbiology, 2020 - frontiersin.org
Human endogenous retroviruses (HERVs) are derived from exogenous retrovirus infections
in the evolution of primates and account for about 8% of the human genome. They were …
in the evolution of primates and account for about 8% of the human genome. They were …