Description and optimization of a multiplex bead-based flow cytometry method (MBFCM) to characterize extracellular vesicles in serum samples from patients with …

L Li, A Görgens, V Mussack, E Pepeldjiyska… - Cancer Gene …, 2022 - nature.com
Abstract Extracellular Vesicles (EVs) are membranous vesicles produced by all cells under
physiological and pathological conditions. In hematological malignancies, tumor-derived …

High serum levels of extracellular vesicles expressing malignancy-related markers are released in patients with various types of hematological neoplastic disorders

A Caivano, I Laurenzana, L De Luca, F La Rocca… - Tumor Biology, 2015 - Springer
Many cell types release extracellular vesicles (EVs), including exosomes, microvesicles
(MVs), and apoptotic bodies, which play a role in physiology and diseases. Presence and …

[HTML][HTML] Circulating cancer stem cell-derived extracellular vesicles as a novel biomarker for clinical outcome evaluation

D Brocco, P Lanuti, P Simeone, G Bologna… - Journal of …, 2019 - hindawi.com
The recent introduction of the “precision medicine” concept in oncology pushed cancer
research to focus on dynamic measurable biomarkers able to predict responses to novel …

Bead‐Based Extracellular Vesicle Analysis Using Flow Cytometry

KS Yang, HY Lin, C Curley, MW Welch… - Advanced …, 2020 - Wiley Online Library
Extracellular vesicles (EVs) represent promising circulating biomarkers for cancers, but their
high‐throughput analyses in clinical settings prove challenging due to lack of simple, fast …

Quantification and phenotypic characterization of extracellular vesicles from patients with acute myeloid and B-cell lymphoblastic leukemia

M Miljkovic-Licina, N Arraud, AD Zahra, P Ropraz… - Cancers, 2021 - mdpi.com
Simple Summary Extracellular vesicles (EVs) are lipid bound vesicles secreted by cells into
the extracellular space. They play an important role in cell-to-cell communication by …

Isolation and identification of plasma extracellular vesicles protein biomarkers

MV Lihon, M Hadisurya, X Wu, A Iliuk… - Cancer Systems and …, 2023 - Springer
Extracellular vesicles (EVs) have emerged as a valuable source for disease biomarkers and
an alternative drug delivery system due to their ability to carry cargo and target specific cells …

Multiplexed profiling of biomarkers in extracellular vesicles for cancer diagnosis and therapy monitoring

S Zhou, Y Yang, Y Wu, S Liu - Analytica chimica acta, 2021 - Elsevier
Extracellular vesicles (EVs) are nanoscale vesicles secreted by normal and pathological
cells. The types and levels of surface proteins and internal nucleic acids in EVs are closely …

The Role of Extracellular Vesicles in the Pathogenesis of Hematological Malignancies: Interaction with Tumor Microenvironment; a Potential Biomarker and Targeted …

K Das, T Mukherjee, P Shankar - Biomolecules, 2023 - mdpi.com
The tumor microenvironment (TME) plays an important role in the development and
progression of hematological malignancies. In recent years, studies have focused on …

Extracellular vesicles in hematological malignancies: from biomarkers to therapeutic tools

J Khalife, JF Sanchez, F Pichiorri - Diagnostics, 2020 - mdpi.com
Small extracellular vesicles (EVs) are a heterogenous group of lipid particles released by all
cell types in physiological and pathological states. In hematological malignancies, tumor …

[HTML][HTML] Cancer-ID: toward identification of cancer by tumor-derived extracellular vesicles in blood

LG Rikkert, P Beekman, J Caro, FAW Coumans… - Frontiers in …, 2020 - frontiersin.org
Extracellular vesicles (EVs) have great potential as biomarkers since their composition and
concentration in biofluids are disease state dependent and their cargo can contain disease …