Autophagy is a critical regulator of cellular homeostasis and its dysregulation often results in
various disease manifestations, including cancer. Nimbolide, an active chemical constituent …

Of late, nimbolide, a limonoid from the neem tree (Azadirachta indica) has gained increasing
research attention owing to its potent antiproliferative and apoptosis-inducing effects. The …

The mortality and morbidity rates of pancreatic cancer are high because of its extremely
invasive and metastatic nature. Its lack of symptoms, late diagnosis and chemo–resistance …

We aimed to investigate the cytotoxic effects of nimbolide, a limonoid present in leaves and
flowers of the neem tree (Azadirachta indica) on human breast cancer cells. The molecular …

Autophagy inhibition has been widely accepted as a promising therapeutic strategy in
cancer, while the lack of effective and specific autophagy inhibitors hinders its application …

The traditional Chinese medicine bufalin, extracted from toad's skin, has been demonstrated
to exert anticancer activities in various kinds of human cancers. The mechanisms of action …

Bromelain, from pineapple, possesses potent anticancer effects. We investigated autophagic
phenomenon in mammary carcinoma cells (estrogen receptor positive and negative) under …

β, β‐Dimethylacrylshikonin (DMAS) is an anti‐cancer compound extracted from the roots of
Lithospermum erythrorhizon. The present study aims to investigate the effects of DMAS on …

Nimbolide is one of the major compounds from the leaves and flowers of the neem tree and
exhibits antitumor properties on various cancer cells. However, no report has shown that …

Berberine has drawn extensive attention toward their wide range of biochemical and
pharmacological effects, including antineoplastic effect in recent years, but the precise …