Trimethylamine N-oxide (TMAO), diet and cardiovascular disease

MS Thomas, ML Fernandez - Current Atherosclerosis Reports, 2021 - Springer
Abstract Purpose of Review The association between plasma Trimethylamine N-Oxide
(TMAO), diet and risk for cardiovascular disease (CVD) is still not fully understood. While …

[HTML][HTML] Relationship of serum trimethylamine N-oxide (TMAO) levels with early atherosclerosis in humans

E Randrianarisoa, A Lehn-Stefan, X Wang, M Hoene… - Scientific reports, 2016 - nature.com
Abstract Circulating trimethylamine N-Oxide (TMAO) levels predict cardiovascular disease
(CVD), possibly by impacting on cholesterol metabolism and oxidative stress. Because …

[HTML][HTML] Plasma trimethylamine N-oxide concentration is associated with choline, phospholipids, and methyl metabolism

R Obeid, HM Awwad, Y Rabagny, S Graeber… - The American journal of …, 2016 - Elsevier
Background: Elevated plasma concentrations of the gut bacteria choline metabolite
trimethylamine N-oxide (TMAO) are associated with atherosclerosis. However, the …

Urinary levels of trimethylamine‐N‐oxide and incident coronary heart disease: a prospective investigation among urban Chinese adults

D Yu, XO Shu, ES Rivera, X Zhang, Q Cai… - Journal of the …, 2019 - Am Heart Assoc
Background Trimethylamine‐N‐oxide (TMAO), a diet‐derived, gut microbial–host
cometabolite, has been associated with adverse cardiovascular outcomes in patient …

Trimethylamine N-oxide and risk of cardiovascular disease and mortality

C Kanitsoraphan, P Rattanawong, S Charoensri… - Current nutrition …, 2018 - Springer
Abstract Purpose of Review Trimethylamine N-oxide (TMAO) is a gut microbiota-dependent
metabolite produced from choline and phosphatidylcholine. Trimethylamine N-oxide was …

[HTML][HTML] Effects of lifestyle intervention on plasma trimethylamine N-oxide in obese adults

ML Erickson, SK Malin, Z Wang, JM Brown, SL Hazen… - Nutrients, 2019 - mdpi.com
Accumulating evidence linking trimethylamine N-oxide (TMAO) to cardiovascular disease
(CVD) risk has prompted interest in developing therapeutic strategies to reduce its …

Circulating trimethylamine N‐oxide and the risk of cardiovascular diseases: a systematic review and meta‐analysis of 11 prospective cohort studies

J Qi, T You, J Li, T Pan, L Xiang… - Journal of cellular and …, 2018 - Wiley Online Library
Circulating trimethylamine N‐oxide (TMAO), a canonical metabolite from gut flora, has been
related to the risk of cardiovascular disorders. However, the association between circulating …

The relationship between trimethylamine-N-oxide and prevalent cardiovascular disease in a multiethnic population living in Canada

A Mente, K Chalcraft, H Ak, AD Davis, E Lonn… - Canadian Journal of …, 2015 - Elsevier
Background Microflora-dependent trimethylamine-N-oxide (TMAO) formation, which results
from intake of choline and L-carnitine-rich food, shows promise as a predictor of …

[HTML][HTML] Circulating trimethylamine N-oxide in association with diet and cardiometabolic biomarkers: an international pooled analysis

JJ Yang, XO Shu, DM Herrington, SC Moore… - The American journal of …, 2021 - Elsevier
ABSTRACT Background Trimethylamine N-oxide (TMAO), a diet-derived, gut microbial-host
cometabolite, has been linked to cardiometabolic diseases. However, the relations remain …

[HTML][HTML] Trimethylamine-N-oxide has prognostic value in coronary heart disease: a meta-analysis and dose-response analysis

ME Yao, PD Liao, XJ Zhao, L Wang - BMC cardiovascular disorders, 2020 - Springer
Background Previous clinical studies have suggested that trimethylamine-N-oxide (TMAO)
could contribute to the development of atherosclerosis cardiovascular disease. However, the …