The high heterogeneity of breast cancer (BC) caused by pathogenic gene mutations poses a
challenge to immunotherapy, but the underlying mechanism remains unknown. The …

Background: This study aimed to investigate the TP53 mutation, its potential immune
features, its prognostic value, and its impact on immune infiltration in patients with breast …

According to statistics 2020, female breast cancer (BRCA) became the most commonly
diagnosed malignancy worldwide. Prognosis of BRCA patients is still poor, especially in …

Background Breast cancer has a high tumor-specific death rate and poor prognosis. In this
study, we aimed to provide a basis for the prognostic risk in patients with breast cancer using …

Background. Although immunotherapy has recently achieved clinical successes in a variety
of cancers, thus far there is no immunotherapeutic strategy for breast cancer (BC). Thus, it is …

Background Tumor microenvironment is composed of a largely altered extracellular matrix
with different cell types. The complex interplay between macrophages and tumor cells …

Purpose Elucidation of the oncogenic role of SLC35A2 in human tumors and the potential
function and clinical significance in breast cancer. Methods Pan-cancer analysis was …

Background Accumulating evidence implies that autophagy plays a critical role in breast
cancer development and progression. It is crucial to screen out autophagy-related encoding …

Purpose Solute carrier family 7, member 5 (SLC7A5) is reportedly a key gene in various
tumors. However, the relationship between SLC7A5 and immune cell infiltration in breast …

Purpose Breast cancer (BC) is the most prevalent malignant tumor worldwide among
women, with the highest incidence rate. The mechanisms underlying nucleotide metabolism …