Chitosan–sEPDM and Melatonin–Chitosan–sEPDM Composite Membranes for Melatonin Transport and Release

FM Păncescu, AAKK Rikabi, OC Oprea, AR Grosu… - Membranes, 2023 - mdpi.com
Melatonin is the hormone that focuses the attention of the researchers in the medical,
pharmaceutical, materials, and membranes fields due to its multiple biomedical implications …

Melatonin-loaded silica coated with hydroxypropyl methylcellulose phthalate for enhanced oral bioavailability: Preparation, and in vitro-in vivo evaluation

Y Li, X Zhao, Y Zu, L Wang, W Wu, Y Deng, C Zu… - European Journal of …, 2017 - Elsevier
Melatonin (MLT) is a small molecule with low water solubility and high permeability.
According to the Biopharmaceutics Classification System, MLT is a class II drug exhibiting a …

[HTML][HTML] The characteristics and biological activity enhancements of melatonin encapsulations for skin care product applications

P Phanphothong, N Kanpipit… - International Journal of …, 2023 - Elsevier
Melatonin (MLT) exhibits antioxidant, ultraviolet protection, anti-inflammatory, and anti-aging
properties. However, its effectiveness is limited by instability, a short half-life, and …

Melatonin-loaded lecithin/chitosan nanoparticles: Physicochemical characterisation and permeability through Caco-2 cell monolayers

A Hafner, J Lovrić, D Voinovich… - International journal of …, 2009 - Elsevier
In this study, the potential of lecithin/chitosan nanoparticles (NPs) as a mucoadhesive
colloidal nanosystem for transmucosal delivery of melatonin was investigated. The size, zeta …

Melatonin-loaded nanocarriers: New horizons for therapeutic applications

LGA Chuffa, FRF Seiva, AA Novais, VA Simão… - Molecules, 2021 - mdpi.com
The use of nanosized particles has emerged to facilitate selective applications in medicine.
Drug-delivery systems represent novel opportunities to provide stricter, focused, and fine …

Characterization of pH-sensitive chitosan/hydroxypropyl methylcellulose composite nanoparticles for delivery of melatonin in cancer therapy

H Jafari, M Hassanpour, A Akbari, J Rezaie, G Gohari… - Materials Letters, 2021 - Elsevier
This work describes the development of novel pH-sensitive nanoparticles (NPs) for the
delivery of melatonin (MLT) in breast cancer therapy. The MLT was encapsulated in …

Transdermal delivery of a pineal hormone: melatonin via elastic liposomes

V Dubey, D Mishra, A Asthana, NK Jain - Biomaterials, 2006 - Elsevier
Melatonin (MT) is a good candidate for transdermal delivery considering its short biological
half-life, low molecular weight and a variable oral absorption. The objective of this work was …

Antioxidant nanoplatforms for dermal delivery: melatonin

A Sanchez Milan… - Current Drug …, 2017 - ingentaconnect.com
Background: Melatonin is emerging as a promising therapeutic agent, mainly due to its role
as antioxidant. Substantial evidences show that melatonin is potentially effective in a variety …

Preparation and characterization of chitosan/LDH composite membranes for drug delivery application

ER Radu, AM Pandele, C Tuncel, F Miculescu, SI Voicu - Membranes, 2023 - mdpi.com
In this study, composite membranes based on chitosan (CS), layered double hydroxide
(LDH), and diclofenac were prepared via dispersing of LDH and diclofenac (DCF) in the …

Evaluation of stability and in vitro wound healing potential of melatonin loaded (lipid enriched) chitosan based microspheres

M Duvnjak Romić, A Sušac, J Lovrić… - Acta …, 2019 - hrcak.srce.hr
Sažetak The aim of this study was to evaluate long-term stability and assess the wound
healing potential of the innovative melatonin-loaded lipid-enriched hybrid system compared …