Insights into the molecular mechanisms regulating mammalian hair cell regeneration
Z Hu, A Singh, II Dennis Bojrab… - Current Opinion in …, 2021 - journals.lww.com
Insights into the molecular mechanisms regulating mammalian... : Current Opinion in
Otolaryngology & Head and Neck Surgery Insights into the molecular mechanisms …
Otolaryngology & Head and Neck Surgery Insights into the molecular mechanisms …
Strategies to regenerate hair cells: identification of progenitors and critical genes
Deafness commonly results from a lesion of the sensory cells and/or of the neurons of the
auditory part of the inner ear. There are currently no treatments designed to halt or reverse …
auditory part of the inner ear. There are currently no treatments designed to halt or reverse …
Molecular pathways modulating sensory hair cell regeneration in adult mammalian cochleae: Progress and perspectives
Noise-induced, drug-related, and age-related disabling hearing loss is a major public health
problem and affect approximately 466 million people worldwide. In non-mammalian …
problem and affect approximately 466 million people worldwide. In non-mammalian …
Concise review: regeneration in mammalian cochlea hair cells: help from supporting cells transdifferentiation
B Franco, B Malgrange - Stem Cells, 2017 - academic.oup.com
It is commonly assumed that mammalian cochlear cells do not regenerate. Therefore, if hair
cells are lost following an injury, no recovery could occur. However, during the first postnatal …
cells are lost following an injury, no recovery could occur. However, during the first postnatal …
Hair cell regeneration
Y Chen, S Zhang, R Chai, H Li - Hearing loss: Mechanisms, prevention …, 2019 - Springer
Cochlear hair cells are mechanoreceptors of the auditory system and cannot spontaneously
regenerate in adult mammals; thus hearing loss due to hair cell damage is permanent. In …
regenerate in adult mammals; thus hearing loss due to hair cell damage is permanent. In …
Manipulating cell fate in the cochlea: a feasible therapy for hearing loss
Mammalian auditory hair cells do not spontaneously regenerate, unlike hair cells in lower
vertebrates, including fish and birds. In mammals, hearing loss due to the loss of hair cells is …
vertebrates, including fish and birds. In mammals, hearing loss due to the loss of hair cells is …
[HTML][HTML] Hair Cell Regeneration: From Animals to Humans
Cochlear hair cells convert sound into electrical signals that are relayed via the spiral
ganglion neurons to the central auditory pathway. Hair cells are vulnerable to damage …
ganglion neurons to the central auditory pathway. Hair cells are vulnerable to damage …
Hair cell fate decisions in cochlear development and regeneration
DA Cotanche, CL Kaiser - Hearing research, 2010 - Elsevier
The discovery of avian cochlear hair cell regeneration in the late 1980s and the concurrent
development of new techniques in molecular and developmental biology generated a …
development of new techniques in molecular and developmental biology generated a …
Hair cell regeneration
ASB Edge, ZY Chen - Current opinion in neurobiology, 2008 - Elsevier
The mammalian inner ear largely lacks the capacity to regenerate hair cells, the sensory
cells required for hearing and balance. Recent studies in both lower vertebrates and …
cells required for hearing and balance. Recent studies in both lower vertebrates and …
[HTML][HTML] Research progress on the mechanism of cochlear hair cell regeneration
S Xu, N Yang - Frontiers in Cellular Neuroscience, 2021 - frontiersin.org
Mammalian inner ear hair cells do not have the ability to spontaneously regenerate, so their
irreversible damage is the main cause of sensorineural hearing loss. The damage and loss …
irreversible damage is the main cause of sensorineural hearing loss. The damage and loss …