Background Neonatal hypoxic ischaemic encephalopathy due to perinatal asphyxia, can
result in severe neurodevelopmental disability or mortality. Hypothermia is at present the …

Objective: Therapeutic hypothermia (TH) is the current standard of care for neonatal hypoxic-
ischemic encephalopathy (HIE), yet morbidity and mortality remain significant. Adjuvant …

Context: Therapeutic hypothermia is the recommended treatment for neonates with
moderate or severe hypoxic ischemic encephalopathy (HIE). There is an increasing trend to …

Background: Therapeutic hypothermia provides up to 30% neuroprotection in moderate to
severe hypoxic ischemic encephalopathy (HIE). Additional neuroprotection may be …

Representing an important cause of long–term disability, term neonatal hypoxic-ischemic
encephalopathy (HIE) urgently needs further research aimed at repurposing existing drug as …

Background We investigated the safety of therapeutic hypothermia during intervention in
infants with hypoxic-ischemic encephalopathy (HIE). Methods The MEDLINE, EMBASE …

With mounting evidence that hypothermia is neuroprotective in newborns with hypoxic-
ischemic encephalopathy (HIE), an increasing number of centers are offering this therapy …

Objective To establish the evidence of therapeutic hypothermia for newborns with hypoxic
ischemic encephalopathy (HIE). Data Sources Cochrane Central Register of Controlled …

Hypoxia-ischemia in the perinatal period is a serious condition affecting infants, which can
result in death and cerebral palsy and associated disabilities. There has been significant …

Abstract Purpose of Review Therapeutic hypothermia reduces death or disability in term and
near-term infants with moderate-severe hypoxic-ischemic encephalopathy. Nevertheless …