CRISPR is widely considered to be a disruptive technology. However, when it comes to the
most controversial topic, germline genome editing (GGE), there is no consensus on whether …

This paper explores the ethics of introducing genome-editing technologies as a new
reproductive option. In particular, it focuses on whether genome editing can be considered a …

Following the birth in 2018 of two babies from embryos altered using CRISPR-Cas9, human
germline gene editing (GGE) moved from abstract concern to reality. He Jiankui, the scientist …

Europe is resolutely on its way to reaffirming a 20-year-old policy banning all inheritable
interventions involving the human genome. This approach, which was well justified two …

Abstract Background Clustered Regularly Interspaced Short Palindromic Repeats-
associated (CRISPR-Cas) technology may allow for efficient and highly targeted gene …

The current kerfuffle around the use of CRISPR/Cas9 and other gene editing technologies in
human germline research is the latest in a series of related controversies at the intersection …

Abstract Germline Gene Editing (GGE) has enormous potential both as a research tool and a
therapeutic intervention. While other types of gene editing are relatively uncontroversial …

Recent studies using gene editing tools such as CRISPR/Cas9 have shown an enormously
broad spectrum of possible future applications. This genetic engineering technique allows …

With CRISPR/Cas9 and other genome-editing technologies, successful somatic and
germline genome editing are becoming feasible. To respond, an American Society of …

Genome editing allows for the versatile genetic modification of somatic cells, germ cells and
embryos. In particular, CRISPR/Cas9 is worldwide used in biomedical research. Although …