DNA methylation in peripheral blood: a potential biomarker for cancer molecular epidemiology
Aberrant DNA methylation is associated with cancer development and progression. There
are several types of specimens from which DNA methylation pattern can be measured and …
are several types of specimens from which DNA methylation pattern can be measured and …
[HTML][HTML] Blood-based DNA methylation signatures in cancer: A systematic review
Y Li, Z Fan, Y Meng, S Liu, H Zhan - … Acta (BBA)-Molecular Basis of Disease, 2023 - Elsevier
DNA methylation profiles are in dynamic equilibrium via the initiation of methylation,
maintenance of methylation and demethylation, which control gene expression and …
maintenance of methylation and demethylation, which control gene expression and …
DNA methylation as clinically useful biomarkers—light at the end of the tunnel
VV Levenson, AA Melnikov - Pharmaceuticals, 2012 - mdpi.com
A recent expansion of our knowledge about epigenetic changes strongly suggests that
epigenetic rather than genetic features better reflect disease development, and …
epigenetic rather than genetic features better reflect disease development, and …
DNA Methylation as a Cancer‐Specific Biomarker: From Molecules to Populations
A Patel, JD Groopman, A Umar - … of the New York Academy of …, 2003 - Wiley Online Library
Cancer contributes to a large proportion of the mortality and morbidity in the United States
and worldwide. Despite advances in diagnosis and treatment of various cancers, early …
and worldwide. Despite advances in diagnosis and treatment of various cancers, early …
Blood-based DNA methylation as biomarker for breast cancer: a systematic review
Q Tang, J Cheng, X Cao, H Surowy, B Burwinkel - Clinical epigenetics, 2016 - Springer
Multiple studies have investigated global DNA methylation profiles and gene-specific DNA
methylation in blood-based DNA to develop powerful screening markers for cancer. This …
methylation in blood-based DNA to develop powerful screening markers for cancer. This …
Methylated DNA as a possible screening marker for neoplastic disease in several body fluids
HM Müller, M Widschwendter - Expert Review of Molecular …, 2003 - Taylor & Francis
Early detection appears to be one of the most important approaches to reducing mortality
caused by neoplasia. Changes in DNA methylation have been recognized as one of the …
caused by neoplasia. Changes in DNA methylation have been recognized as one of the …
Analysis of DNA methylation status in bodily fluids for early detection of cancer
K Yokoi, K Yamashita, M Watanabe - International journal of molecular …, 2017 - mdpi.com
Epigenetic alterations by promoter DNA hypermethylation and gene silencing in cancer
have been reported over the past few decades. DNA hypermethylation has great potential to …
have been reported over the past few decades. DNA hypermethylation has great potential to …
Analysis of DNA methylation in cancer: location revisited
A Koch, SC Joosten, Z Feng, TC de Ruijter… - Nature reviews Clinical …, 2018 - nature.com
Abstract Changes in DNA methylation in cancer have been heralded as promising targets
for the development of powerful diagnostic, prognostic, and predictive biomarkers. Despite …
for the development of powerful diagnostic, prognostic, and predictive biomarkers. Despite …
Global DNA hypomethylation in peripheral blood leukocytes as a biomarker for cancer risk: a meta-analysis
HD Woo, J Kim - PloS one, 2012 - journals.plos.org
Background Good biomarkers for early detection of cancer lead to better prognosis.
However, harvesting tumor tissue is invasive and cannot be routinely performed. Global …
However, harvesting tumor tissue is invasive and cannot be routinely performed. Global …
[HTML][HTML] Methylation profiling of normal individuals reveals mosaic promoter methylation of cancer-associated genes
LS Kristensen, M Raynor, I Candiloro, A Dobrovic - Oncotarget, 2012 - ncbi.nlm.nih.gov
Epigenetic silencing by promoter methylation of genes associated with cancer initiation and
progression is a hallmark of tumour cells. As a consequence, testing for DNA methylation …
progression is a hallmark of tumour cells. As a consequence, testing for DNA methylation …